Search results
- 1.0570547 - FGÚ 2024 RIV DE eng J - Journal Article
Pavluch, Vojtěch - Engstová, Hana - Špačková, Jitka - Ježek, Petr
Deficiency of transcription factor Nkx6.1 does not prevent insulin secretion in INS-1E cells.
Scientific Reports. Roč. 13, č. 1 (2023), č. článku 683. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA MŠMT(CZ) LX22NPO5104; GA ČR(CZ) GA20-00408S
Institutional support: RVO:67985823
Keywords : Nkx6.1 * pancreatic-beta-cells * GLUT2 * pyruvate carboxylase * glucose-stimulated insulin secretion
OECD category: Endocrinology and metabolism (including diabetes, hormones)
Impact factor: 4.6, year: 2022
Method of publishing: Open access
https://doi.org/10.1038/s41598-023-27985-7
Permanent Link: https://hdl.handle.net/11104/0341847File Download Size Commentary Version Access 23_0021_0570547.pdf 0 4.4 MB Publisher’s postprint open-access - 2.0532352 - FGÚ 2021 RIV US eng J - Journal Article
Plecitá-Hlavatá, Lydie - Engstová, Hana - Holendová, Blanka - Tauber, Jan - Špaček, Tomáš - Petrásková, Lucie - Křen, Vladimír - Špačková, Jitka - Gotvaldová, Klára - Ježek, Jan - Dlasková, Andrea - Smolková, Katarína - Ježek, Petr
Mitochondrial Superoxide Production Decreases on Glucose-Stimulated Insulin Secretion in Pancreatic beta Cells Due to Decreasing Mitochondrial Matrix NADH/NAD(+) Ratio.
Antioxidants & Redox Signaling. Roč. 33, č. 12 (2020), s. 789-815. ISSN 1523-0864. E-ISSN 1557-7716
R&D Projects: GA ČR(CZ) GA16-06700S; GA ČR(CZ) GA17-01813S; GA ČR(CZ) GA20-00408S
Institutional support: RVO:67985823 ; RVO:61388971
Keywords : mitochondrial superoxide generation * pancreatic beta cells * glucose-stimulated insulin secretion * Complex I * NADH/NAD(+) ratio * fluorescence lifetime imaging
OECD category: Endocrinology and metabolism (including diabetes, hormones); Analytical chemistry (MBU-M)
Impact factor: 8.401, year: 2020
Method of publishing: Open access
https://www.liebertpub.com/doi/10.1089/ars.2019.7800
Permanent Link: http://hdl.handle.net/11104/0310854 - 3.0532331 - FGÚ 2021 RIV GB eng J - Journal Article
Kahancová, Anežka - Sklenář, Filip - Ježek, Petr - Dlasková, Andrea
Overexpression of native IF1 downregulates glucose-stimulated insulin secretion by pancreatic INS-1E cells.
Scientific Reports. Roč. 10, č. 1 (2020), č. článku 1551. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA ČR(CZ) GA17-08565S; GA MŠMT(CZ) LM2015062
Institutional support: RVO:67985823
Keywords : IF1 * ATP synthase * glucose-stimulated insulin secretion * type 2 diabetes * INS-1E cells * beta-cells
OECD category: Biochemistry and molecular biology
Impact factor: 4.380, year: 2020
Method of publishing: Open access
https://www.nature.com/articles/s41598-020-58411-x
Permanent Link: http://hdl.handle.net/11104/0310838 - 4.0531801 - FGÚ 2021 RIV CH eng J - Journal Article
Leguina-Ruzzi, Alberto A. - Vodičková, Anežka - Holendová, Blanka - Pavluch, Vojtěch - Tauber, Jan - Engstová, Hana - Dlasková, Andrea - Ježek, Petr
Glucose-Induced Expression of DAPIT in Pancreatic beta-Cells.
Biomolecules. Roč. 10, č. 7 (2020), č. článku 1026. E-ISSN 2218-273X
R&D Projects: GA ČR(CZ) GA20-00408S
Institutional support: RVO:67985823
Keywords : mitochondria * USMG5/DAPIT * glucose-stimulated insulin secretion * glucose-induced expression * membrane subunits of ATP synthase * ATP synthase oligomers mitochondrial cristae morphology
OECD category: Endocrinology and metabolism (including diabetes, hormones)
Impact factor: 4.879, year: 2020
Method of publishing: Open access
https://www.mdpi.com/2218-273X/10/7/1026
Permanent Link: http://hdl.handle.net/11104/0310418 - 5.0531109 - FGÚ 2021 RIV US eng J - Journal Article
Plecitá-Hlavatá, Lydie - Jabůrek, Martin - Holendová, Blanka - Tauber, Jan - Pavluch, Vojtěch - Berková, Z. - Cahová, M. - Schröder, K. - Brandes, R. P. - Siemen, D. - Ježek, Petr
Glucose-Stimulated Insulin Secretion Fundamentally Requires H(2)O(2)Signaling by NADPH Oxidase 4.
Diabetes. Roč. 69, č. 7 (2020), s. 1341-1354. ISSN 0012-1797. E-ISSN 1939-327X
R&D Projects: GA ČR(CZ) GA20-00408S; GA ČR(CZ) GA16-06700S; GA ČR(CZ) GA17-01813S
Institutional support: RVO:67985823
Keywords : glucose-stimulated insulin secretion * NADPH oxidase NOX4 * ATP-sensitive potassium channel * cytosolic H2O2 redox signaling * beta-cell-specific NOX4 knockout mice * 2-oxo-isocaproate
OECD category: Endocrinology and metabolism (including diabetes, hormones)
Impact factor: 9.461, year: 2020
Method of publishing: Open access
https://doi.org/10.2337/db19-1130
Permanent Link: http://hdl.handle.net/11104/0309847 - 6.0451864 - FGÚ 2016 RIV US eng J - Journal Article
Ježek, Jan - Dlasková, Andrea - Zelenka, Jaroslav - Jabůrek, Martin - Ježek, Petr
H2O2-Activated Mitochondrial Phospholipase iPLA2 gamma Prevents Lipotoxic Oxidative Stress in Synergy with UCP2, Amplifies Signaling via G-Protein-Coupled Receptor GPR40, and Regulates Insulin Secretion in Pancreatic beta-Cells.
Antioxidants & Redox Signaling. Roč. 23, č. 12 (2015), s. 958-972. ISSN 1523-0864. E-ISSN 1557-7716
R&D Projects: GA ČR(CZ) GPP303/11/P320; GA ČR(CZ) GA13-02033S; GA ČR(CZ) GA13-06666S; GA ČR GA15-02051S
Institutional support: RVO:67985823
Keywords : mitochondrial phospholipase iPLA2 gamma * uncoupling protein UCP2 * G-protein coupled receptor - 40 * glucose-stimulated insulin secretion * pancreatic beta cells
Subject RIV: FB - Endocrinology, Diabetology, Metabolism, Nutrition
Impact factor: 7.093, year: 2015
Permanent Link: http://hdl.handle.net/11104/0252926 - 7.0428036 - FGÚ 2015 RIV CZ eng J - Journal Article
Ježek, Petr - Olejár, Tomáš - Smolková, Katarína - Ježek, Jan - Dlasková, Andrea - Plecitá-Hlavatá, Lydie - Zelenka, Jaroslav - Špaček, Tomáš - Engstová, Hana - Reguera Pajuelo, David - Jabůrek, Martin
Antioxidant and regulatory role of mitochondrial uncoupling protein UCP2 in pancreatic beta-cells.
Physiological Research. Roč. 63, Suppl.1 (2014), S73-S91. ISSN 0862-8408. E-ISSN 1802-9973
R&D Projects: GA ČR(CZ) GAP302/10/0346; GA ČR(CZ) GAP305/12/1247; GA ČR(CZ) GPP304/10/P204; GA MŠMT(CZ) EE2.3.30.0025
Institutional support: RVO:67985823
Keywords : mitochondria * uncoupling protein UCP2 * pancreatic beta-cells * reactive oxygen species * glucose-stimulated insulin secretion
Subject RIV: EA - Cell Biology
Impact factor: 1.293, year: 2014
Permanent Link: http://hdl.handle.net/11104/0233445 - 8.0321505 - FGÚ 2009 GB eng A - Abstract
Ježek, Petr - Hlavatá, Lydie - Špaček, Tomáš
Superoxide generation is diminished during glucose-stimulated insulin secretion in INS-1E cells.
[Produkce superoxidu je snížená během sekrece inzulínu indukované glukózou u INS-1E buněk.]
FEBS Journal. Roč. 275, Suppl.1 (2008), s. 310-310. ISSN 1742-464X. E-ISSN 1742-4658.
[FEBS Congress /33./ and IUBMB Conference /11./. 28.06.2008-03.07.2008, Athens]
R&D Projects: GA MZd(CZ) NR7917; GA AV ČR(CZ) IAA500110701
Institutional research plan: CEZ:AV0Z50110509
Keywords : cpo1 * superoxide production * glucose-stimulated insulin secretion * INS-1E cells
Subject RIV: ED - Physiology
Permanent Link: http://hdl.handle.net/11104/0170015 - 9.0321498 - FGÚ 2009 NL eng A - Abstract
Špaček, Tomáš - Hlavatá, Lydie - Ježek, Petr
Mitochondrial superoxide generation is diminished during glucose-stimulated insulin secretion in INS-1E cells.
[Tvorba mitochondriálního superoxidu je potlačena během glukózou stimulované sekrece inzulínu v INS-1E buňkách.]
Biochimica Et Biophysica Acta-Bioenergetics. Elsevier. Roč. 1777, Suppl. (2008), S48-S48. ISSN 0005-2728. E-ISSN 1879-2650.
[European Bioenergetics Conference /15./. 19.07.2008-24.07.2008, Dublin]
R&D Projects: GA AV ČR(CZ) IAA500110701; GA MZd NR9183
Institutional research plan: CEZ:AV0Z50110509
Keywords : cpo1 * superoxide * INS-1E cells * glucose-stimulated insulin secretion
Subject RIV: ED - Physiology
Permanent Link: http://hdl.handle.net/11104/0170009 - 10.0309981 - FGÚ 2009 RIV GB eng J - Journal Article
Špaček, Tomáš - Šantorová, Jitka - Zacharovová, K. - Berková, Z. - Hlavatá, Lydie - Saudek, F. - Ježek, Petr
Glucose-stimulated insulin secretion of insulinoma INS-1E cells is associated with elevation of both respiration and mitochondrial membrane potential.
[Při glukózou stimulované inzulínové sekreci u INS-1E buněk se zvyšuje jak respirace tak mitochondriální membránový potenciál.]
International Journal of Biochemistry and Cell Biology. Roč. 40, č. 8 (2008), s. 1522-1535. ISSN 1357-2725. E-ISSN 1878-5875
R&D Projects: GA MZd(CZ) NR7917
Institutional research plan: CEZ:AV0Z50110509
Keywords : in situ mitochondrial membrane potential * in situ mitochondrial respiration * glucose-stimulated insulin secretion
Subject RIV: FB - Endocrinology, Diabetology, Metabolism, Nutrition
Impact factor: 4.178, year: 2008
Permanent Link: http://hdl.handle.net/11104/0161985