Search results
- 1.0541026 - ÚEB 2022 RIV CZ eng J - Journal Article
Spicakova, A. - Kraus, Petr - Gucký, Tomáš - Kryštof, Vladimír - Strnad, Miroslav - Bazgier, V. - Otyepka, M. - Kubickova, V. - Poruba, M. - Rácová, Z. - Zapletalová, I. - Anzenbacher, P.
in vitro and in silico Studies of Interaction of Synthetic 2,6,9-Trisubstituted Purine Kinase Inhibitors BPA-302, BP-21 and BP-117 With Liver Drug-Metabolizing Cytochromes P450.
Physiological Research. Roč. 69, SEP (2020), s. 627-636. ISSN 0862-8408. E-ISSN 1802-9973
R&D Projects: GA MZd(CZ) NV17-28231A
Institutional support: RVO:61389030
Keywords : r-roscovitine * cell-cycle * cancer * series * Cytochrome P450 inhibition * High performance liquid chromatography * Cyclin-dependent kinase inhibitor * FLT3-ITD inhibitor * Drug metabolism
OECD category: Organic chemistry
Impact factor: 1.881, year: 2020
Method of publishing: Open access
https://www.biomed.cas.cz/physiolres/pdf/2020/69_S627.pdf
Permanent Link: http://hdl.handle.net/11104/0318600File Download Size Commentary Version Access 2020_Spicakova_Physiological Research_S627.pdf 1 2.5 MB Other open-access - 2.0504625 - ÚEB 2020 RIV GR eng J - Journal Article
Kubczak, M. - Szustka, A. - Błoński, J. Z. - Gucký, T. - Misiewicz, M. - Kryštof, Vladimír - Robak, Z. - Rogalińska, M.
Dose and drug changes in chronic lymphocytic leukemia cell response in vitro: A comparison of standard therapy regimens with two novel cyclin‑dependent kinase inhibitors.
Molecular Medicine Reports. Roč. 19, č. 5 (2019), s. 3593-3603. ISSN 1791-2997. E-ISSN 1791-3004
R&D Projects: GA MŠMT(CZ) LO1204; GA ČR(CZ) GA15-15264S
Institutional support: RVO:61389030
Keywords : Alkylator * Anticancer agents * Apoptosis * Chronic lymphocytic leukemia * Cyclin-dependent kinase inhibitor * In vitro cell incubations * Monoclonal antibody * Necrosis * Viability
OECD category: Hematology
Impact factor: 2.100, year: 2019
Method of publishing: Open access
http://doi.org/10.3892/mmr.2019.10007
Permanent Link: http://hdl.handle.net/11104/0296211File Download Size Commentary Version Access 2019_Kubczak_MOLECULAR MEDICINE REPORTS_3593.pdf 0 1.9 MB Other open-access - 3.0492257 - ÚEB 2019 RIV US eng J - Journal Article
Cherukupalli, S. - Chandrasekaran, B. - Kryštof, Vladimír - Aleti, R.R. - Sayyad, N. - Merugu, S.R. - Kushwaha, N.D. - Karpoormath, R.
Synthesis, anticancer evaluation, and molecular docking studies of some novel 4,6-disubstituted pyrazolo[3,4-d]pyrimidines as cyclin-dependent kinase 2 (CDK2) inhibitors.
Bioorganic Chemistry. Roč. 79, SEP (2018), s. 46-59. ISSN 0045-2068. E-ISSN 1090-2120
R&D Projects: GA MŠMT(CZ) LO1204; GA ČR GA17-14007S
Institutional support: RVO:61389030
Keywords : cancer-therapy * cell-cycle * cyclin-dependent-kinase-2 * roscovitine * lethality * scaffold * targets * mice * Pyrazolo[3,4-d]pyrimidine * Cyclin dependent kinase inhibitor * Anti-proliferative activity * Molecular docking * glide
OECD category: Oncology
Impact factor: 3.926, year: 2018
Permanent Link: http://hdl.handle.net/11104/0285792File Download Size Commentary Version Access 2018_Cherukupalli_BIOORGANIC CHEMISTRY_46.pdf 2 1.1 MB Other open-access - 4.0491930 - ÚEB 2019 RIV NL eng J - Journal Article
Široká, Jitka - Čečková, M. - Urbánek, Lubor - Kryštof, Vladimír - Gucký, Tomáš - Hofman, J. - Strnad, Miroslav - Štaud, F.
LC-MS/MS method for determination of cyclin-dependent kinase inhibitors, BP-14 and BP-20, and its application in pharmacokinetic study in rat.
Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences. Roč. 1089, JUL 1 (2018), s. 24-32. ISSN 1570-0232. E-ISSN 1873-376X
R&D Projects: GA ČR GA17-14007S
Institutional support: RVO:61389030
Keywords : seliciclib r-roscovitine * hepatocellular-carcinoma * metabolism * potent * cdc2 * Cyclin-dependent kinase inhibitor * bp-14 * bp-20 * Pharmacokinetics * Tissue distribution
OECD category: Analytical chemistry
Impact factor: 2.813, year: 2018
Permanent Link: http://hdl.handle.net/11104/0285531File Download Size Commentary Version Access 2018_Siroka_JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES_24.pdf 3 995.1 KB Other open-access - 5.0343928 - ÚEB 2011 RIV CH eng J - Journal Article
Kryštof, Vladimír - McNae, I. W. - Walkinshaw, M. D. - Fischer, P.M. - Müller, P. - Vojtešek, B. - Orság, Martin - Havlíček, Libor - Strnad, Miroslav
Antiproliferative activity of olomoucine II, a novel 2,6,9-trisubstituted purine cyclin-dependent kinase inhibitor.
Cellular and Molecular Life Sciences. Roč. 62, č. 15 (2005), s. 1763-1771. ISSN 1420-682X. E-ISSN 1420-9071
R&D Projects: GA ČR GP204/03/D231
Institutional research plan: CEZ:AV0Z50380511
Keywords : olomoucine II * roscovitine * cyclin-dependent kinase inhibitor
Subject RIV: CE - Biochemistry
Impact factor: 4.582, year: 2005
Permanent Link: http://hdl.handle.net/11104/0186288 - 6.0083394 - ÚEB 2008 RIV CZ eng J - Journal Article
Anzenbacherová, E. - Janalík, J. - Popa, Igor - Strnad, Miroslav - Anzenbacher, P.
INTERACTION OF AROMATIC CYTOKININS WITH HUMAN LIVER MICROSOMAL CYTOCHROMES P450.
[INTERACTION OF AROMATIC CYTOKININS WITH HUMAN LIVER MICROSOMAL CYTOCHROMES P450.]
Biomedical Papers. Roč. 149, č. 2 (2005), s. 349-351. ISSN 1213-8118. E-ISSN 1804-7521
Institutional research plan: CEZ:AV0Z50380511
Keywords : Cytokinins * Cyclin dependent kinase inhibitor * Cytochrome P450
Subject RIV: CE - Biochemistry
http://publib.upol.cz/~obd/fulltext/Biomed/2005/2/349.pdf
Permanent Link: http://hdl.handle.net/11104/0146654