Search results
- 1.0563377 - ÚEB 2023 RIV NL eng J - Journal Article
Kuczynska, K. - Bończak, B. - Rárová, L. - Kvasnicová, M. - Strnad, Miroslav - Pakulski, Z. - Cmoch, P. - Fiałkowski, M.
Synthesis and cytotoxic activity of 1,2,3-triazoles derived from 2,3-seco-dihydrobetulin via a click chemistry approach.
Journal of Molecular Structure. Roč. 1250, č. 1 (2022), č. článku 131751. ISSN 0022-2860. E-ISSN 1872-8014
R&D Projects: GA ČR(CZ) GA20-25308S
Institutional support: RVO:61389030
Keywords : 5-Thiotetrazole * Betulin * Click chemistry * Cytotoxicity * Lupane * sar * Triazole
OECD category: Medicinal chemistry
Impact factor: 3.8, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.molstruc.2021.131751
Permanent Link: https://hdl.handle.net/11104/0335358File Download Size Commentary Version Access 2022_Kuczynska_JOURNAL OF MOLECULAR STRUCTURE_131751.pdf 1 3.2 MB Other open-access - 2.0546173 - ÚEB 2022 RIV FR eng J - Journal Article
Gonzalez, Gabriel - Hodoň, J. - Kazakova, A. - D'Acunto, Cosimo Walter - Kaňovský, P. - Urban, M. - Strnad, Miroslav
Novel pentacyclic triterpenes exhibiting strong neuroprotective activity in SH-SY5Y cells in salsolinol- and glutamate-induced neurodegeneration models.
European Journal of Medicinal Chemistry. Roč. 213, MAR 5 (2021), č. článku 113168. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA ČR GA20-15621S
Institutional support: RVO:61389030
Keywords : Betulin * Betulinic acid * Caspase-3,7 * Glutamate * Mitochondria * Neuroprotection * Pentacyclic triterpenes * Salsolinol * SH-SY5Y cells * Triazole
OECD category: Biochemistry and molecular biology
Impact factor: 7.088, year: 2021
Method of publishing: Open access
http://doi.org/10.1016/j.ejmech.2021.113168
Permanent Link: http://hdl.handle.net/11104/0322712File Download Size Commentary Version Access 2021_Gonzalez_EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY_113168.pdf 1 4.3 MB Other open-access - 3.0531674 - ÚEB 2021 RIV US eng J - Journal Article
Korda, A. - Rárová, Lucie - Pakulski, Z. - Strnad, Miroslav - Oklešťková, Jana - Kuczynska, K. - Cmoch, P. - Gwardiak, K. - Karczewski, R.
New lupane bidesmosides exhibiting strong cytotoxic activities in vitro.
Bioorganic Chemistry. Roč. 100, JUL (2020), č. článku 103868. ISSN 0045-2068. E-ISSN 1090-2120
R&D Projects: GA ČR(CZ) GA20-25308S
Institutional support: RVO:61389030
Keywords : Betulin bidesmosides * Birch bark * Cytotoxic activity * Structure–activity relationship * Synthesis
OECD category: Medicinal chemistry
Impact factor: 5.275, year: 2020
Method of publishing: Open access
http://doi.org/10.1016/j.bioorg.2020.103868
Permanent Link: http://hdl.handle.net/11104/0310291File Download Size Commentary Version Access 2020_Korda_BIOORGANIC CHEMISTRY_103868.pdf 1 701.4 KB Other open-access - 4.0429932 - ÚEB 2015 RIV GB eng J - Journal Article
Cmoch, P. - Korda, A. - Rárová, Lucie - Oklešťková, Jana - Strnad, Miroslav - Luboradzki, R. - Pakulski, Z.
Synthesis and structure-activity relationship study of cytotoxic lupane-type 3 beta-O-monodesmosidic saponins with an extended C-28 side chain.
Tetrahedron. Roč. 70, č. 17 (2014), s. 2717-2730. ISSN 0040-4020. E-ISSN 1464-5416
R&D Projects: GA MŠMT(CZ) LO1204
Institutional support: RVO:61389030
Keywords : BETULIN DERIVATIVES * SECONDARY ALCOHOLS * ANTITUMOR-ACTIVITY
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 2.641, year: 2014
Permanent Link: http://hdl.handle.net/11104/0234895File Download Size Commentary Version Access 2014_Cmoch_TETRAHEDRON_2717.pdf 1 982.1 KB Other open-access - 5.0398914 - ÚOCHB 2014 RIV HU eng J - Journal Article
Vlk, M. - Urban, M. - Elbert, Tomáš - Šarek, J.
Synthesis of selectively deuterated and tritiated lupane derivatives with cytotoxic activity.
Journal of Radioanalytical and Nuclear Chemistry. Roč. 298, č. 2 (2013), s. 1149-1157. ISSN 0236-5731. E-ISSN 1588-2780
Grant - others:GA ČR(CZ) GA305/09/1216
Institutional support: RVO:61388963
Keywords : isotopic labelling * tritium * deuterium * betulin * betulinic acid * cytotoxicity
Subject RIV: CB - Analytical Chemistry, Separation
Impact factor: 1.415, year: 2013
Permanent Link: http://hdl.handle.net/11104/0226393 - 6.0395459 - MBÚ 2014 RIV CH eng J - Journal Article
Biedermann, David - Urban, M. - Buděšínský, Miloš - Kvasnica, Miroslav - Šarek, J.
Study of addition of difluorocarbene on double bond of triterpenes.
Journal of Fluorine Chemistry. Roč. 148, APR (2013), s. 30-35. ISSN 0022-1139. E-ISSN 1873-3328
Institutional support: RVO:61388963 ; RVO:61388971
Keywords : Triterpenes * Betulin * Difluorocarbene
Subject RIV: CE - Biochemistry
Impact factor: 1.952, year: 2013
Permanent Link: http://hdl.handle.net/11104/0223501 - 7.0381976 - ÚOCHB 2013 CZ eng A - Abstract
Vlk, M. - Micolová, P. - Švehláková, T. - Šarek, J. - Elbert, Tomáš - Džubák, P. - Hajduch, M.
Selectively labelled betulinines.
Chemické listy. Česká společnost chemická. Roč. 106, - (2012), s722-s722. ISSN 0009-2770. E-ISSN 1213-7103.
[EuCheMS Chemistry Congress /4./. 26.08.2012-30.08.2012, Prague]
Institutional research plan: CEZ:AV0Z40550506
Keywords : betulin * triterpenoids
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0212329 - 8.0322112 - ÚEB 2009 RIV NL eng J - Journal Article
Cmoch, P. - Pakulski, Z. - Swaczynová, Jana - Strnad, Miroslav
Synthesis of lupane-type saponins bearing mannosyl and 3,6-branched trimannosyl residues and their evaluation as anticancer agents.
[Syntéza saponinů lupanového typu nesoucích manosyl a 3,6 rozvětvený trimanosylový zbytek a jejich využítí jako protinádorová léčiva.]
Carbohydrate Research. Roč. 343, č. 6 (2008), s. 995-1003. ISSN 0008-6215. E-ISSN 1873-426X
Institutional research plan: CEZ:AV0Z50380511
Keywords : Saponin * Betulin * Lupeol * Betulinic acid
Subject RIV: CE - Biochemistry
Impact factor: 1.960, year: 2008
Permanent Link: http://hdl.handle.net/11104/0170458 - 9.0084714 - ÚOCHB 2008 RIV US eng J - Journal Article
Urban, Milan - Šarek, J. - Kvasnica, Miroslav - Tišlerová, I. - Hajduch, M.
Triterpenoid pyrazines and benzopyrazines with cytotoxic activity.
[Triterpenoidní pyraziny a benzopyraziny s cytotoxickou aktivitou.]
Journal of Natural Products. Roč. 70, č. 4 (2007), s. 526-532. ISSN 0163-3864. E-ISSN 1520-6025
R&D Projects: GA MŠMT(CZ) LC06070
Grant - others:GA ČR(CZ) GP203/03/D152; GAČR(CZ) GP203/05/P025
Program: GP
Institutional research plan: CEZ:AV0Z40550506
Keywords : triterpenoid * pyrazine * cytotoxicity * betulin
Subject RIV: CC - Organic Chemistry
Impact factor: 2.551, year: 2007
Permanent Link: http://hdl.handle.net/11104/0147407