Search results

  1. 1.
    0583653 - BC 2024 RIV US eng J - Journal Article
    Schwark, M. - Yerena, Jose Alberto Martinez - Roehrborn, K. - Hrouzek, P. - Divoká, P. - Štenclová, Lenka - Delawská, K. - Enke, H. - Vorreiter, C. - Wiley, F. - Sippl, W. - Sobotka, R. - Saha, S. - Wilde, S. B. - Mareš, Jan - Niedermeyer, T. H. J.
    More than just an eagle killer: The freshwater cyanobacterium iAetokthonos hydrillicola/i produces highly toxic dolastatin derivatives.
    Proceedings of the National Academy of Sciences of the United States of America. Roč. 120, č. 40 (2023), č. článku e2219230120. ISSN 0027-8424. E-ISSN 1091-6490
    R&D Projects: GA ČR(CZ) GC19-21649J
    Institutional support: RVO:60077344
    Keywords : antineoplastic agents * anticancer * inhibition * tubulin * cyanotoxin * cytotoxicity * aetokthonostatin * dolastatin
    OECD category: Marine biology, freshwater biology, limnology
    Impact factor: 11.1, year: 2022
    Method of publishing: Open access
    https://doi.org/10.1073/pnas.2219230120
    Permanent Link: https://hdl.handle.net/11104/0351681
     
     
  2. 2.
    0582359 - MBÚ 2024 RIV US eng J - Journal Article
    Schwark, M. - Martinez Yerena, Jose A. - Roehrborn, K. - Hrouzek, Pavel - Divoká, Petra - Štenclová, L. - Delawská, Kateřina - Enke, H. - Vorreiter, C. - Wiley, F. - Sippl, W. - Sobotka, Roman - Saha, Subhasish - Wilde, Susan B. - Mareš, Jan - Niedermeyer, T. H. J.
    More than just an eagle killer: The freshwater cyanobacterium Aetokthonos hydrillicola produces highly toxic dolastatin derivatives.
    Proceedings of the National Academy of Sciences of the United States of America. Roč. 120, č. 40 (2023), č. článku e2219230120. ISSN 0027-8424. E-ISSN 1091-6490
    R&D Projects: GA ČR(CZ) GC19-21649J
    Institutional support: RVO:61388971
    Keywords : antineoplastic agents * marine * anticancer * analog * inhibition * tubulin * biosynthesis * efficacy * targets * binding * cyanotoxin * cytotoxicity * aetokthonostatin * dolastatin * biosynthesis
    OECD category: Microbiology
    Impact factor: 11.1, year: 2022
    Method of publishing: Open access
    https://www.pnas.org/doi/10.1073/pnas.2219230120
    Permanent Link: https://hdl.handle.net/11104/0350572
     
     
  3. 3.
    0562052 - ÚEB 2023 RIV US eng J - Journal Article
    Jorda, R. - Havlíček, Libor - Peřina, M. - Vojáčková, V. - Pospíšil, T. - Djukic, Stefan - Škerlová, Jana - Grúz, J. - Renešová, N. - Klener, P. - Řezáčová, Pavlína - Strnad, Miroslav - Kryštof, V.
    3,5,7-Substituted Pyrazolo[4,3- d]Pyrimidine Inhibitors of Cyclin-Dependent Kinases and Cyclin K Degraders.
    Journal of Medicinal Chemistry. Roč. 65, č. 13 (2022), s. 8881-8896. ISSN 0022-2623. E-ISSN 1520-4804
    R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA ČR(CZ) GA20-25308S
    Institutional support: RVO:61389030 ; RVO:61388963
    Keywords : Antineoplastic Agents * Cell Line * Cyclin-Dependent Kinases
    OECD category: Organic chemistry
    Impact factor: 7.3, year: 2022
    Method of publishing: Limited access
    https://doi.org/10.1021/acs.jmedchem.1c02184
    Permanent Link: https://hdl.handle.net/11104/0334472
    FileDownloadSizeCommentaryVersionAccess
    2022_Jorda_JOURNAL OF MEDICINAL CHEMISTRY_8881.pdf39 MBOtherrequire
     
     
  4. 4.
    0475066 - ÚACH 2018 RIV GB eng J - Journal Article
    Štenglová Netíková, I. R. - Slušná, Michaela - Tolasz, Jakub - Šťastný, Martin - Popelka, Štěpán - Štengl, Václav
    A new possible way of anthracycline cytostatics decontamination.
    New Journal of Chemistry. Roč. 41, č. 10 (2017), s. 3975-3985. ISSN 1144-0546. E-ISSN 1369-9261
    Institutional support: RVO:61388980 ; RVO:61389013
    Keywords : performance liquid-chromatography * sulfur mustard * photocatalytic degradation * antineoplastic agents * aqueous-solution * warfare agents * doxorubicin * anticancer
    OECD category: Inorganic and nuclear chemistry; Polymer science (UMCH-V)
    Impact factor: 3.201, year: 2017
    Permanent Link: http://hdl.handle.net/11104/0271947
     
     
  5. 5.
    0457446 - BTÚ 2016 RIV US eng J - Journal Article
    Klučková, Katarína - Dong, L. F. - Bajziková, Martina - Rohlena, Jakub - Neužil, Jiří
    Evaluation of respiration of mitochondria in cancer cells exposed to mitochondria-targeted agents.
    Methods in molecular biology. Roč. 1265, 07 Oct 2015 (2015), s. 181-194. ISSN 1940-6029
    R&D Projects: GA MŠMT(CZ) ED1.1.00/02.0109
    Institutional support: RVO:86652036
    Keywords : Animals * Antineoplastic Agents * drug effects * *pharmacology
    Subject RIV: EB - Genetics ; Molecular Biology
    Permanent Link: http://hdl.handle.net/11104/0257845
     
     


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