Search results
- 1.0582665 - ÚOCHB 2025 RIV eng J - Journal Article
Galkin, Maksym - Priss, Anastasiia - Kyriukha, Y. - Shvadchak, V.
Navigating α-Synuclein Aggregation Inhibition: Methods, Mechanisms, and Molecular Targets.
Chemical Record. Roč. 24, č. 2 (2024), č. článku e202300282. ISSN 1527-8999. E-ISSN 1528-0691
Institutional support: RVO:61388963
Keywords : amyloid * inhibitor * alpha-synuclein * Parkinson's disease * protein misfolding
Impact factor: 6.6, year: 2022
Method of publishing: Limited access
https://doi.org/10.1002/tcr.202300282
Permanent Link: https://hdl.handle.net/11104/0350744 - 2.0578423 - ÚFCH JH 2025 RIV GB eng J - Journal Article
Das, D. - Bharadwaz, Priyam - Mattaparthi, V. S. K.
Computational investigation on the effect of the peptidomimetic inhibitors (NPT100-18A and NPT200-11) on the α-synuclein and lipid membrane interactions.
Journal of Biomolecular Structure & Dynamics. (2023). ISSN 0739-1102
Institutional support: RVO:61388955
Keywords : molecular-dynamics simulations * lewy body disease * parkinsons-disease * force-field * basis-sets * system * oligomerization * accumulation * mutations * mechanism * alpha-Synuclein aggregation * membrane dynamics * dft * npt100-18a * npt200-11
OECD category: Physical chemistry
Impact factor: 4.4, year: 2022
Method of publishing: Limited access
https://www.tandfonline.com/doi/abs/10.1080/07391102.2023.2262599
Permanent Link: https://hdl.handle.net/11104/0347420 - 3.0550581 - BTÚ 2023 RIV CH eng J - Journal Article
Raghavan, A. - Rao, P. - Neužil, Jiří - Pountney, D. L. - Nath, S.
Oxidative stress and Rho GTPases in the biogenesis of tunnelling nanotubes: implications in disease and therapy.
Cellular and Molecular Life Sciences. Roč. 79, č. 1 (2022). ISSN 1420-682X. E-ISSN 1420-9071
Institutional support: RVO:86652036
Keywords : mesenchymal stem-cells * fibrillar alpha-synuclein * multipotent stromal cells * mitochondrial transfer * in-vitro * membrane nanotubes
OECD category: Biochemistry and molecular biology
Impact factor: 8, year: 2022
Method of publishing: Open access
https://link.springer.com/article/10.1007/s00018-021-04040-0
Permanent Link: http://hdl.handle.net/11104/0331072 - 4.0543753 - ÚPT 2022 RIV US eng J - Journal Article
Khairnar, A. - Rudá-Kučerová, J. - Arab, A. - Hadjistyllis, C. - Šejnoha Minsterová, A. - Shang, Q. - Chovsepian, A. - Dražanová, Eva - Szabó, N. - Starčuk jr., Zenon - Rektorová, I. - Pan-Montojo, F.
Diffusion kurtosis imaging detects the time-dependent progress of pathological changes in the oral rotenone mouse model of Parkinson's disease.
Journal of Neurochemistry. Roč. 158, č. 3 (2021), s. 779-797. ISSN 0022-3042. E-ISSN 1471-4159
R&D Projects: GA MŠMT(CZ) LM2015062; GA MŠMT(CZ) EF16_013/0001775
EU Projects: European Commission(XE) 291782 - SOMOPRO II
Institutional support: RVO:68081731
Keywords : alpha synuclein * diffusion kurtosis imaging * MRI * Parkinson * rotenone's disease * tract-based spatial statistics
OECD category: Medical laboratory technology (including laboratory samples analysis
Impact factor: 5.546, year: 2021
Method of publishing: Open access
https://onlinelibrary.wiley.com/doi/10.1111/jnc.15449
Permanent Link: http://hdl.handle.net/11104/0325478 - 5.0536187 - ÚFCH JH 2021 RIV CH eng J - Journal Article
Scollo, Federica - La Rosa, C.
Amyloidogenic Intrinsically Disordered Proteins: New Insights into Their Self-Assembly and Their Interaction with Membranes.
Life. Roč. 10, č. 8 (2020), č. článku 144. E-ISSN 2075-1729
R&D Projects: GA ČR(CZ) GX19-26854X
Institutional support: RVO:61388955
Keywords : alpha-synuclein aggregation * mammalian prion protein * in-vitro conversion * a-beta * precursor protein * lipid-membranes * parkinsons-disease * molecular-dynamics * fibril formation * nmr structure * intrinsically disordered proteins * lipid * membrane * cmc * amyloids
OECD category: Physical chemistry
Impact factor: 3.817, year: 2020
Method of publishing: Open access
Permanent Link: http://hdl.handle.net/11104/0313998File Download Size Commentary Version Access 0536187.pdf 1 1.9 MB open access Publisher’s postprint open-access - 6.0533119 - BTÚ 2021 RIV US eng J - Journal Article
Valdinocci, D. - Kovářová, Jaromíra - Neužil, Jiří - Pountney, D. L.
Alpha-Synuclein Aggregates Associated with Mitochondria in Tunnelling Nanotubes.
Neurotoxicity Research. SEP 2020, SEP 2020 (2020). ISSN 1029-8428. E-ISSN 1476-3524
Institutional support: RVO:86652036
Keywords : Alpha-synuclein * Parkinson's disease * Tunnelling nanotube
OECD category: Neurosciences (including psychophysiology
Impact factor: 3.911, year: 2020
Method of publishing: Open access
https://link.springer.com/article/10.1007/s12640-020-00285-y
Permanent Link: http://hdl.handle.net/11104/0313127 - 7.0521553 - BTÚ 2020 RIV GB eng J - Journal Article
Valdinocci, D. - Simões, R. F. - Kovářová, Jaromíra - Cunha-Oliveira, T. - Neužil, Jiří - Pountney, D. L.
Intracellular and Intercellular Mitochondrial Dynamics in Parkinson’s Disease.
Frontiers in Neuroscience. Roč. 13, SEP 18 2019 (2019), č. článku 930. E-ISSN 1662-4548
Institutional support: RVO:86652036
Keywords : alpha-synuclein * mitochondria * mitophagy * Parkinson’s * tunneling nanotube
OECD category: Neurosciences (including psychophysiology
Impact factor: 3.648, year: 2018
Method of publishing: Open access
https://www.frontiersin.org/articles/10.3389/fnins.2019.00930/full
Permanent Link: http://hdl.handle.net/11104/0306151 - 8.0502034 - ÚOCHB 2019 GB eng A - Abstract
Kurochka, Andrii - Shvadchak, Volodymyr - Yushchenko, Dmytro A.
Lipids inhibit aggregation of alpha-synuclein.
FEBS Open Bio. Wiley. Roč. 8, Suppl 1 (2018), s. 395. ISSN 2211-5463. E-ISSN 2211-5463.
[FEBS Congress /43./ Biochemistry Forever. 07.07.2018-12.07.2018, Prague]
Institutional support: RVO:61388963
Keywords : alpha-synuclein * lipids
OECD category: Biochemistry and molecular biology
Permanent Link: http://hdl.handle.net/11104/0293986 - 9.0490459 - ÚOCHB 2019 RIV DE eng J - Journal Article
Shvadchak, Volodymyr V. - Afitska, Kseniia - Yushchenko, Dmytro A.
Inhibition of alpha-Synuclein Amyloid Fibril Elongation by Blocking Fibril Ends.
Angewandte Chemie - International Edition. Roč. 57, č. 20 (2018), s. 5690-5694. ISSN 1433-7851. E-ISSN 1521-3773
R&D Projects: GA ČR(CZ) GJ18-06255Y
Institutional support: RVO:61388963
Keywords : alpha-synuclein * amyloid fibrils * inhibitors * kinetics * neurodegenerative disorders
OECD category: Biophysics
Impact factor: 12.257, year: 2018
Permanent Link: http://hdl.handle.net/11104/0284697 - 10.0485440 - ÚOCHB 2018 RIV US eng J - Journal Article
Afitska, Kseniia - Fučíková, A. - Shvadchak, Volodymyr V. - Yushchenko, Dmytro A.
Modification of C Terminus Provides New Insights into the Mechanism of alpha-Synuclein Aggregation.
Biophysical Journal. Roč. 113, č. 10 (2017), s. 2182-2191. ISSN 0006-3495. E-ISSN 1542-0086
Institutional support: RVO:61388963
Keywords : alpha-synuclein * aggregation * kinetics
OECD category: Biophysics
Impact factor: 3.495, year: 2017
Permanent Link: http://hdl.handle.net/11104/0280467