Search results
- 1.0572295 - ÚMG 2024 RIV CH eng J - Journal Article
Kahveci-Tuerkoez, S. - Blaesius, K. - Wozniak, J. - Rinkens, C. - Seifert, A. - Kašpárek, Petr - Ohm, H. - Oltzen, S. - Nieszporek, M. - Schwarz, N. - Babendreyer, A. - Preisinger, C. - Sedláček, Radislav - Ludwig, A. - Duesterhoeft, S.
A structural model of the iRhom-ADAM17 sheddase complex reveals functional insights into its trafficking and activity.
Cellular and Molecular Life Sciences. Roč. 80, č. 5 (2023), č. článku 135. ISSN 1420-682X. E-ISSN 1420-9071
R&D Projects: GA MŠMT(CZ) LM2018126
Institutional support: RVO:68378050
Keywords : iRhom * adam17 * Ectodomain shedding * TNF signalling * EGFR ligand release iRhom-ADAM17 complex structure * iRhom homology domain
OECD category: Biochemistry and molecular biology
Impact factor: 8, year: 2022
Method of publishing: Open access
https://link.springer.com/article/10.1007/s00018-023-04783-y
Permanent Link: https://hdl.handle.net/11104/0343044 - 2.0572291 - ÚOCHB 2024 RIV NL eng J - Journal Article
Amin, A. - Badenes, M. - Tüshaus, J. - de Carvalho, É. - Burbridge, E. - Faísca, P. - Trávníčková, Květa - Barros, A. - Carobbio, S. - Domingos, P. M. - Vidal-Puig, A. - Moita, L. F. - Maguire, S. - Stříšovský, Kvido - Ortega, F.J. - Fernández-Real, J. M. - Lichtenthaler, S. F. - Adrain, C.
Semaphorin 4B is an ADAM17-cleaved adipokine that inhibits adipocyte differentiation and thermogenesis.
Molecular Metabolism. Roč. 73, July (2023), č. článku 101731. ISSN 2212-8778. E-ISSN 2212-8778
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : ADAM17/TACE * metabolism * adipose tissue * thermogenesis * Semaphorin4B Sema4b * obesity * cold challenge * beta-adrenoceptor signalling
OECD category: Biochemistry and molecular biology
Impact factor: 8.1, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.molmet.2023.101731
Permanent Link: https://hdl.handle.net/11104/0343039 - 3.0544132 - ÚMG 2022 RIV CH eng J - Journal Article
Dusterhoft, S. - Kahveci-Tuerkoez, S. - Wozniak, J. - Seifert, A. - Kašpárek, Petr - Ohm, H. - Liu, S. - Kopkanová, Jana - Lokau, J. - Garbers, C. - Preisinger, C. - Sedláček, Radislav - Freeman, M. - Ludwig, A.
The iRhom homology domain is indispensable for ADAM17-mediated TNF alpha and EGF receptor ligand release.
Cellular and Molecular Life Sciences. Roč. 78, č. 11 (2021), s. 5015-5040. ISSN 1420-682X. E-ISSN 1420-9071
Institutional support: RVO:68378050
Keywords : iRhom * adam17 * Ectodomain shedding * tnf * Growth factors * iRhom homology domain
OECD category: Biochemistry and molecular biology
Impact factor: 9.234, year: 2021
Method of publishing: Open access
https://link.springer.com/article/10.1007/s00018-021-03845-3
Permanent Link: http://hdl.handle.net/11104/0321178 - 4.0539726 - ÚMG 2021 RIV CH eng J - Journal Article
Seifert, A. - Wozniak, J. - Duesterhoeft, S. - Kašpárek, Petr - Sedláček, Radislav - Dreschers, S. - Orlikowsky, T.W. - Yildiz, D. - Ludwig, A.
The iRhom2/ADAM17 Axis Attenuates Bacterial Uptake by Phagocytes in a Cell Autonomous Manner.
International Journal of Molecular Sciences. Roč. 21, č. 17 (2020), č. článku 5978. E-ISSN 1422-0067
R&D Projects: GA MŠMT(CZ) LM2015040; GA MŠMT(CZ) LM2018126; GA MŠMT ED2.1.00/19.0395
Institutional support: RVO:68378050
Keywords : necrosis-factor-alpha * mycobacterium-tuberculosis * adam17 deficiency * tnf-alpha * disintegrin * inflammation * neutrophils * activation * receptor * irhom2 * metalloproteinase * adam17 * iRhom2 * bacterial phagocytosis * inflammation * infection * shedding * chemokines * phagocytes
OECD category: Microbiology
Impact factor: 5.924, year: 2020
Method of publishing: Open access
https://www.mdpi.com/1422-0067/21/17/5978
Permanent Link: http://hdl.handle.net/11104/0317429 - 5.0422658 - ÚMG 2014 RIV GB eng J - Journal Article
Buryová, Halka - Chalupský, Karel - Žbodáková, Olga - Kanchev, Ivan - Jiroušková, Markéta - Gregor, Martin - Sedláček, Radislav
Liver protective effect of ursodeoxycholic acid includes regulation of ADAM17 activity.
BMC Gastroenterology. Roč. 13, 30.10.2013 (2013), s. 155-155. E-ISSN 1471-230X
R&D Projects: GA ČR GAP305/10/2143; GA ČR GAP303/10/2044; GA AV ČR IAA500520812; GA MŠMT ED1.1.00/02.0109
Institutional support: RVO:68378050
Keywords : ursodeoxycholic acid * ADAM17 * shedding * cholestasis * liver
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 2.113, year: 2013
Permanent Link: http://hdl.handle.net/11104/0228827File Download Size Commentary Version Access 0422658.pdf 4 1.3 MB Publisher’s postprint require