Search results
- 1.0585467 - MBÚ 2025 RIV NL eng J - Journal Article
Lepesheva, Anna - Grobarčíková, Michaela - Osičková, Adriana - Jurnečka, David - Knoblochová, Šárka - Čížková, Monika - Osička, Radim - Šebo, Peter - Mašín, Jiří
Modification of the RTX domain cap by acyl chains of adapted length rules the formation of functional hemolysin pores.
Biochimica Et Biophysica Acta-Biomembranes. Roč. 1866, č. 5 (2024), s. 184311. ISSN 0005-2736. E-ISSN 1879-2642
R&D Projects: GA ČR(CZ) GA22-15825S; GA ČR(CZ) GA22-01558S; GA ČR(CZ) GX19-27630X; GA MŠMT(CZ) LX22NPO5103; GA MŠMT(CZ) EH22_008/0004597
Research Infrastructure: EATRIS-CZ IV - 90253; CIISB III - 90242
Institutional support: RVO:61388971
Keywords : RTX toxin * Adenylate cyclase toxin * α-Hemolysin * Chimera * Fatty acylation * Cytotoxicity
OECD category: Microbiology
Impact factor: 3.4, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0005273624000427?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0353157File Download Size Commentary Version Access Modification of the RTX.pdf 0 3 MB Publisher’s postprint open-access
Research data: the ProteomeXchange Consortium via the PRIDE partner repository with the data set identifier PXD046160 - 2.0573968 - MBÚ 2024 RIV NL eng J - Journal Article
Osičková, Adriana - Knoblochová, Šárka - Bumba, Ladislav - Man, Petr - Kalaninová, Zuzana - Lepesheva, Anna - Jurnečka, David - Čížková, Monika - Biedermannová, Lada - Goldsmith, J. A. - Maynard, J. A. - McLellan, J. S. - Osička, Radim - Šebo, Peter - Mašín, Jiří
A conserved tryptophan in the acylated segment of RTX toxins controls their βinf2/inf integrin–independent cell penetration.
Journal of Biological Chemistry. Roč. 299, č. 8 (2023), č. článku 104978. ISSN 0021-9258. E-ISSN 1083-351X
R&D Projects: GA ČR(CZ) GA22-01558S; GA ČR(CZ) GA22-01558S; GA MŠMT(CZ) LX22NPO5103; GA MŠMT(CZ) EF18_046/0015974; GA ČR(CZ) GX19-27630X
Research Infrastructure: e-INFRA CZ - 90140; EATRIS-CZ IV - 90253; CIISB III - 90242
Institutional support: RVO:61388971 ; RVO:86652036
Keywords : acylated segment * adenylate cyclase toxin * cytotoxicity * hydrogen/deuterium exchange * RTX toxin * thermal stability * tryptophan residue * α-hemolysin * β integrins 2
OECD category: Microbiology
Impact factor: 4.8, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0021925823020069?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0344352 - 3.0556379 - MBÚ 2023 RIV CH eng J - Journal Article
Filipi, Kateřina - Rahman, Waheed Ur - Osičková, Adriana - Osička, Radim
Kingella kingae RtxA Cytotoxin in the Context of Other RTX Toxins.
Microorganisms. Roč. 10, č. 3 (2022), č. článku 518. E-ISSN 2076-2607
R&D Projects: GA ČR(CZ) GA22-15825S
Institutional support: RVO:61388971
Keywords : escherichia-coli-hemolysin * adenylate-cyclase toxin * aggregatibacter-actinomycetemcomitans leukotoxin * pasteurella-haemolytica leukotoxin * real-time pcr * polymerase-chain-reaction * outer-membrane vesicles * bordetella-pertussis cyaa * terminal secretion signal * cell-invasive activity * beta(2) integrins * Kingella kingae * membrane * pore-forming * RtxA * RTX toxin
OECD category: Microbiology
Impact factor: 4.5, year: 2022
Method of publishing: Open access
https://www.mdpi.com/2076-2607/10/3/518
Permanent Link: http://hdl.handle.net/11104/0331349 - 4.0555862 - ÚMG 2022 RIV CH eng J - Journal Article
Holubová, J. - Juhasz, Attila - Mašín, J. - Staněk, O. - Jurnečka, D. - Osičková, A. - Šebo, P. - Osička, R.
Selective Enhancement of the Cell-Permeabilizing Activity of Adenylate Cyclase Toxin Does Not Increase Virulence of Bordetella pertussis.
International Journal of Molecular Sciences. Roč. 22, č. 21 (2021), č. článku 11655. E-ISSN 1422-0067
R&D Projects: GA MŠMT(CZ) LM2018126; GA MŠMT EF18_046/0015861
Research Infrastructure: CCP II - 90126
Institutional support: RVO:68378050
Keywords : Adenylate cyclase toxin * Bordetella pertussis * CAMP intoxication * Lung colonization * Lung inflammation * Pore-forming activity * RTX toxin * Virulence
OECD category: Microbiology
Impact factor: 6.208, year: 2021
Method of publishing: Open access
https://www.mdpi.com/1422-0067/22/21/11655
Permanent Link: http://hdl.handle.net/11104/0330464 - 5.0549727 - MBÚ 2022 RIV CH eng J - Journal Article
Holubová, Jana - Juhasz, Attila - Mašín, Jiří - Staněk, Ondřej - Jurnečka, David - Osičková, Adriana - Šebo, Peter - Osička, Radim
Selective enhancement of the cell-permeabilizing activity of adenylate cyclase toxin does not increase virulence of bordetella pertussis.
International Journal of Molecular Sciences. Roč. 22, č. 21 (2021), č. článku 11655. E-ISSN 1422-0067
R&D Projects: GA MŠMT(CZ) LM2018133; GA ČR(CZ) GA19-12695S
Research Infrastructure: CIISB II - 90127; CCP II - 90126
Institutional support: RVO:61388971
Keywords : Adenylate cyclase toxin * Bordetella pertussis * CAMP intoxication * Lung colonization * Lung inflammation * Pore-forming activity * RTX toxin * Virulence
OECD category: Microbiology
Impact factor: 6.208, year: 2021
Method of publishing: Open access
https://www.mdpi.com/1422-0067/22/21/11655
Permanent Link: http://hdl.handle.net/11104/0325678 - 6.0533024 - MBÚ 2021 RIV US eng J - Journal Article
Mašín, Jiří - Osičková, Adriana - Jurnečka, David - Klímová, Nela - Khaliq, Humaira - Šebo, Peter - Osička, Radim
Retargeting from the CR3 to the LFA-1 receptor uncovers the adenylyl cyclase enzyme?translocating segment ofBordetellaadenylate cyclase toxin.
Journal of Biological Chemistry. Roč. 295, č. 28 (2020), s. 9349-9365. ISSN 0021-9258. E-ISSN 1083-351X
R&D Projects: GA ČR(CZ) GA19-04607S; GA ČR(CZ) GA18-18079S; GA ČR(CZ) GA19-12695S; GA ČR(CZ) GA18-20621S; GA MŠMT(CZ) LM2018133
Institutional support: RVO:61388971
Keywords : AC domain translocation * acylation * acyltransferase * fatty acyl * integrin * RTX toxin
OECD category: Microbiology
Impact factor: 5.157, year: 2020
Method of publishing: Open access with time embargo
https://www.jbc.org/content/early/2020/05/11/jbc.RA120.013630.short
Permanent Link: http://hdl.handle.net/11104/0311527