Search results
- 1.0531731 - ÚEB 2021 RIV FR eng J - Journal Article
Šíša, Miroslav - Dvořáková, Marcela - Temml, V. - Jarošová, Veronika - Vaněk, Tomáš - Landa, Přemysl
Synthesis, inhibitory activity and in silico docking of dual COX/5-LOX inhibitors with quinone and resorcinol core.
European Journal of Medicinal Chemistry. Roč. 204, 15 October (2020), č. článku 112620. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA MŠMT(CZ) LTC18065
Grant - others:OPPK(CZ) CZ.2.16/3.1.00/ 21519
Institutional support: RVO:61389030
Keywords : 5-Lipoxygenase * Anti-inflammatory activity * Cyclooxygenase * Quinones * Resorcinols
OECD category: Organic chemistry
Impact factor: 6.514, year: 2020
Method of publishing: Open access
http://doi.org/10.1016/j.ejmech.2020.112620
Permanent Link: http://hdl.handle.net/11104/0310351File Download Size Commentary Version Access 2020_Sisa_European Journal of Medicinal Chemistry_112620.pdf 1 1.5 MB Other open-access - 2.0523510 - ÚOCHB 2021 RIV BR eng J - Journal Article
Urbanová, K. - Klouček, P. - Havlík, J. - Valterová, Irena - Kokoška, L.
Fast and Ecological Liquid-Liquid Separation Method for Preparing Quinones Enriched Extract from Nigella sativa Oil.
Journal of the Brazilian Chemical Society. Roč. 31, č. 4 (2020), s. 739-745. ISSN 0103-5053. E-ISSN 1678-4790
Institutional support: RVO:61388963
Keywords : Nigella sativa * quinones * crude oil * liquid-liquid extraction
OECD category: Analytical chemistry
Impact factor: 1.838, year: 2020
Method of publishing: Open access
http://static.sites.sbq.org.br/jbcs.sbq.org.br/pdf/2019-0067AR.pdf
Permanent Link: http://hdl.handle.net/11104/0307871 - 3.0517349 - ÚEB 2020 RIV CZ cze L - Prototype, f. module
Šíša, Miroslav - Landa, Přemysl - Vaněk, Tomáš
Nová protizánětlivá léčiva založená na přírodních látkách.
[New anti-inflammatory drugs based on natural substances.]
Internal code: DP032016 ; 2018
Technical parameters: Připravené sloučeniny byly charakterizovány pomocí 1H a 13C NMR, MS a elementární analýzy, čistota byla ověřena HPLC/UV. Biochemickým měřením s rekombinantními enzymy byly stanoveny hodnoty IC50 pro vybrané proteinkinázy, které deklarují vysokou aktiviti a selektivitu vůči CDK v řádu nM. In vitro účinnost byla ověřována pomocí MTT/resazurinu, detekcí proliferačních a apoptotických markerů. In vivo účinnost byla ověřena na myším xenotransplantačním modelu. Stanoveny byly základní parametry ADME/T.
Economic parameters: Látky se schopností inhibovat oba pro-zánětlivé enzymy (COX-2 a 5-LOX) jsou považovány za perspektivní při léčbě zánětlivých onemocnění. Získané látky s protizánětlivým účinkem mohou být využity jako nová lěčiva.
R&D Projects: GA TA ČR(CZ) TG03010009
Institutional support: RVO:61389030
Keywords : plant quinones * organic synthesis * anti-inflammatory activity
OECD category: Organic chemistry
Permanent Link: http://hdl.handle.net/11104/0302669 - 4.0359540 - ÚFCH JH 2012 RIV DE eng J - Journal Article
Paretzki, A. - Das, H. S. - Weisser, F. - Scherer, T. - Bubrin, D. - Fiedler, Jan - Nycz, J. E. - Sarkar, B.
Invariant Oxidation State of Copper but not of Ruthenium in Complexes with Noninnocent N-(2-Methyl-5,8-dioxo-5,8-dihydroquinolin-7-yl)acetamide: A Combined Structural, Electrochemical and Spectroelectrochemical Investigation.
European Journal of Inorganic Chemistry. -, č. 15 (2011), s. 2413-2421. ISSN 1434-1948. E-ISSN 1099-0682
R&D Projects: GA ČR GA203/09/0705; GA ČR GA203/08/1157
Institutional research plan: CEZ:AV0Z40400503
Keywords : copper * ruthenium * quinones
Subject RIV: CF - Physical ; Theoretical Chemistry
Impact factor: 3.049, year: 2011
Permanent Link: http://hdl.handle.net/11104/0197314 - 5.0345814 - ÚFCH JH 2011 RIV DE eng J - Journal Article
Das, H. S. - Weisser, F. - Schweinfurth, D. - Su, Ch. Y. - Bogani, C. - Fiedler, Jan - Sarkar, B.
Straightforward Synthesis of Substituted p-Quinones: Isolation of a Key Intermediate and Use as a Bridging Ligand in a Diruthenium Complex.
Chemistry - A European Journal. Roč. 16, č. 10 (2010), s. 2977-2981. ISSN 0947-6539. E-ISSN 1521-3765
R&D Projects: GA MŠMT OC 140; GA MŠMT OC09043
Institutional research plan: CEZ:AV0Z40400503
Keywords : cyclic voltammetry * quinones * ruthenium
Subject RIV: CF - Physical ; Theoretical Chemistry
Impact factor: 5.476, year: 2010
Permanent Link: http://hdl.handle.net/11104/0187001 - 6.0327321 - ÚFCH JH 2010 RIV DE eng J - Journal Article
Das, A. K. - Sarkar, B. - Duboc, C. - Strobel, S. - Fiedler, Jan - Záliš, Stanislav - Lahiri, G. K. - Kaim, W.
An Odd-Electron Complex [Ru-k(NOm)(Q(n))(terpy)](2+) with Two Prototypical Non-Innocent Ligands.
[Komplex [Ruk(NOm)(Qn)(terpy)]2+ s nepárovým elektronem a dvěma prototypickými noninocentními ligandy.]
Angewandte Chemie - International Edition. Roč. 48, č. 23 (2009), s. 4242-4245. ISSN 1433-7851. E-ISSN 1521-3773
R&D Projects: GA AV ČR KAN100400702; GA MŠMT OC 139
Institutional research plan: CEZ:AV0Z40400503
Keywords : nitrosyl complexes * non-innocent ligands * quinones * radical ligands * ruthenium
Subject RIV: CF - Physical ; Theoretical Chemistry
Impact factor: 11.829, year: 2009
Permanent Link: http://hdl.handle.net/11104/0174161 - 7.0321030 - ÚFCH JH 2009 RIV DE eng J - Journal Article
Ghumaan, S. - Sarkar, B. - Maji, S. - Puranik, V. G. - Fiedler, Jan - Urbanos, F. A. - Jimenez-Aparicio, R. - Kaim, W. - Lahiri, G. K.
Valence-State Analysis through Spectroelectrochemistry in a Series of Quinonoid-Bridged Diruthenium Complexes [(acac)(2)Ru(mu-L)Ru(acac)(2)](n) (n =+2,+1, 0,-1,-2).
[Valence-State Analysis through Spectroelectrochemistry in a Series of Quinonoid-Bridged Diruthenium Complexes [(acac)2Ru(.mu.-L)Ru(acac)2]n (n= +2, +1, 0, -1, -2).]
Chemistry - A European Journal. Roč. 14, č. 34 (2008), s. 10816-10828. ISSN 0947-6539. E-ISSN 1521-3765
R&D Projects: GA MŠMT OC 140; GA MŠMT LC510
Institutional research plan: CEZ:AV0Z40400503
Keywords : magnetic properties * quinones * ruthenium * spectroelectrochemistry
Subject RIV: CG - Electrochemistry
Impact factor: 5.454, year: 2008
Permanent Link: http://hdl.handle.net/11104/0169720 - 8.0314803 - ÚOCHB 2009 RIV DE eng J - Journal Article
Rybáček, Jiří - Závada, Jiří - Holý, Petr
Synthesis of extended bifunctional triptycenes.
[Syntéza rozšířených bifunkčních triptycenů.]
Synthesis. -, č. 22 (2008), s. 3615-3618. ISSN 0039-7881. E-ISSN 1437-210X
R&D Projects: GA ČR GA203/03/0087
Institutional research plan: CEZ:AV0Z40550506
Keywords : anthracenes * arynes * Diels-Alder reaction * quinones * triptycenes
Subject RIV: CC - Organic Chemistry
Impact factor: 2.470, year: 2008
Permanent Link: http://hdl.handle.net/11104/0165193 - 9.0181791 - UFCH-W 20030231 CZ eng A - Abstract
Záliš, Stanislav - Kaim, W.
Calculations on Metal-Mediated Tautomerizmus of Substituted Qinones and Quinodiimines-Models of Metal-Dependent Quinoproteins.
Modeling Interactions in Biomolecules. Nové Hrady, 2003. s. 59.
[Workshop on Modeling Interactions in Biomolecules. 15.09.2003-20.09.2003, Nové Hrady]
R&D Projects: GA ČR GA203/03/0821
Institutional research plan: CEZ:AV0Z4040901
Keywords : substituted quinones * quinodiimines * quinoproteins
Subject RIV: CF - Physical ; Theoretical Chemistry
Permanent Link: http://hdl.handle.net/11104/0078309 - 10.0181784 - UFCH-W 20030224 FR eng A - Abstract
Záliš, Stanislav - Kaim, W.
The Modelling of the Metal-Induced Para- to Ortho- Tautomerization of Substituted Quinones and Quinodiimines.
Modelling Chemical Reactivity: from Gas-phase to Solution and Enzymes. Nancy, 2003. s. P67.
[International Conference on Modelling Chemical Reactivity. 16.07.2003-18.07.2003, Nancy]
R&D Projects: GA MŠMT OC D14.20; GA ČR GA203/03/0821
Institutional research plan: CEZ:AV0Z4040901
Keywords : modelling of the metal-induced * quinones * quinodiimines
Subject RIV: CF - Physical ; Theoretical Chemistry
Permanent Link: http://hdl.handle.net/11104/0078302