Search results
- 1.0585854 - ÚMG 2025 RIV CH eng J - Journal Article
Jaervelae, V. - Hamze, M. - Komulainen-Ebrahim, J. - Rahikkala, E. - Piispala, J. - Kallio, M. - Kangas, S. M. - Nickl, Tereza - Huttula, M. - Hinttala, R. - Uusimaa, J. - Medina, I. - Immonen, E.
A novel pathogenic SLC12A5 missense variant in epilepsy of infancy with migrating focal seizures causes impaired KCC2 chloride extrusion.
Frontiers in Molecular Neuroscience. Roč. 17, Apr (2024), č. článku 1372662. ISSN 1662-5099. E-ISSN 1662-5099
Institutional support: RVO:68378050
Keywords : k-cl cotransporter * gaba * expression * phosphorylation * mutation * neurons * server * ph * gaba * potassium-chloride co-transporter * chloride * Cl- * epilepsy * neurodevelopmental disorder
OECD category: Biochemistry and molecular biology
Impact factor: 4.8, year: 2022
Method of publishing: Open access
https://www.frontiersin.org/articles/10.3389/fnmol.2024.1372662/full
Permanent Link: https://hdl.handle.net/11104/0353523 - 2.0570587 - ÚMG 2024 RIV CH eng J - Journal Article
Syding, Linn Amanda - Kubik-Zahorodna, Agnieszka - Reguera, David Pajuelo - Nickl, Petr - Hrušková, Bohdana - Králíková, Michaela - Kopkanová, Jana - Novosadová, Vendula - Kašpárek, Petr - Procházka, Jan - Rozman, Jan - Tureček, Rostislav - Sedláček, Radislav
Ablation of Gabra5 Influences Corticosterone Levels and Anxiety-like Behavior in Mice.
Genes. Roč. 14, č. 2 (2023), č. článku 285. E-ISSN 2073-4425
R&D Projects: GA MŠMT(CZ) LM2018126; GA MŠMT EF16_013/0001789; GA MŠMT EF18_046/0015861; GA MŠMT ED2.1.00/19.0395; GA ČR(CZ) GA19-09283S
EU Projects: European Commission(XE) 765269 - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
Grant - others:AV ČR(CZ) StrategieAV21/29
Program: StrategieAV
Institutional support: RVO:68378041 ; RVO:68378050
Keywords : corticosterone * GABA receptor * anxiety * behavior * mouse model
OECD category: Technologies involving identifying the functioning of DNA, proteins and enzymes and how they influence the onset of disease and maintenance of well-being (gene-based diagnostics and therapeutic interventions (pharmacogenomics, gene-based therapeutics); Neurosciences (including psychophysiology (UEM-P)
Impact factor: 3.5, year: 2022
Method of publishing: Open access
https://www.mdpi.com/2073-4425/14/2/285
Permanent Link: https://hdl.handle.net/11104/0341891 - 3.0558551 - ÚOCHB 2023 RIV US eng J - Journal Article
Solntseva, E. I. - Bukanova, J. V. - Skrebitsky, V. G. - Kudová, Eva
Pregnane neurosteroids exert opposite effects on GABA and glycine-induced chloride current in isolated rat neurons.
Hippocampus. Roč. 32, č. 7 (2022), s. 552-563. ISSN 1050-9631. E-ISSN 1098-1063
R&D Projects: GA MZd(CZ) EF16_025/0007444
Institutional support: RVO:61388963
Keywords : GABA(A) receptor * glycine receptor * neurosteroid * pregnane * structure-activity relationship study
OECD category: Neurosciences (including psychophysiology
Impact factor: 3.5, year: 2022
Method of publishing: Limited access
https://doi.org/10.1002/hipo.23449
Permanent Link: http://hdl.handle.net/11104/0332190 - 4.0557780 - BC 2023 RIV DE eng J - Journal Article
Vadaq, N. - Schirmer, M. - Tunjungputri, R.N. - Vlamakis, H. - Chiriac, Maria-Cecilia - Ardiansyah, E. - Gasem, M. - Joosten, L.A.B. - de Groot, P.G. - Xavier, R.J. - Netea, M.G. - van der Ven, A.J. - de Mast, Q.
Untargeted plasma metabolomics and gut microbiome profiling provide novel insights into the regulation of platelet reactivity in healthy individuals.
Thrombosis and Haemostasis. Roč. 122, č. 04 (2022), s. 529-539. ISSN 0340-6245. E-ISSN 2567-689X
Institutional support: RVO:60077344
Keywords : acid * activation * aggregation * inflammation * inhibition * thrombosis * gaba * camp * metabolome * microbiome * platelet * platelet reactivity
OECD category: Hematology
Impact factor: 6.7, year: 2022
Method of publishing: Limited access
https://doi.org/10.1055/a-1541-3706
Permanent Link: https://hdl.handle.net/11104/0340289 - 5.0551648 - ÚOCHB 2023 RIV CH eng J - Journal Article
Kudová, Eva - Mareš, Pavel - Hill, M. - Vondráková, Kateřina - Tsenov, Grygoriy - Chodounská, Hana - Kubová, Hana - Valeš, Karel
The Neuroactive Steroid Pregnanolone Glutamate: Anticonvulsant Effect, Metabolites and Its Effect on Neurosteroid Levels in Developing Rat Brains.
Pharmaceuticals. Roč. 15, č. 1 (2022), č. článku 49. E-ISSN 1424-8247
R&D Projects: GA MZd(CZ) EF16_025/0007444; GA MZd(CZ) NU20-04-00389
Institutional support: RVO:61388963 ; RVO:67985823
Keywords : neurosteroids * anticonvulsant * zuranolone * NMDA * GABA * metabolomics
OECD category: Organic chemistry
Impact factor: 4.6, year: 2022
Method of publishing: Open access
https://www.mdpi.com/1424-8247/15/1/49
Permanent Link: http://hdl.handle.net/11104/0326887 - 6.0543842 - FGÚ 2022 RIV GB eng J - Journal Article
Patrono, Enrico - Svoboda, Jan - Stuchlík, Aleš
Schizophrenia, the gut microbiota, and new opportunities from optogenetic manipulations of the gut-brain axis.
Behavioral and Brain Functions. Roč. 17, č. 1 (2021), č. článku 7. E-ISSN 1744-9081
R&D Projects: GA ČR(CZ) GA19-03016S; GA ČR(CZ) GA20-00939S; GA MŠMT(CZ) EF19_074/0016409; GA ČR(CZ) GF21-16667K
Institutional support: RVO:67985823
Keywords : schizophrenia * gut microbiota * NMDA hypoactivity * gut optogenetics * NMDARs/GABA interaction * probiotic dietaries * fecal microbiota transplantation
OECD category: Neurosciences (including psychophysiology
Impact factor: 3.950, year: 2021
Method of publishing: Open access
https://doi.org/10.1186/s12993-021-00180-2
Permanent Link: http://hdl.handle.net/11104/0320956 - 7.0542934 - ÚOCHB 2022 RIV CH eng J - Journal Article
Bukanova, J. - Solntseva, E. - Kondratenko, R. - Kudová, Eva
Epipregnanolone as a Positive Modulator of GABAA Receptor in Rat Cerebellar and Hippocampus Neurons.
Biomolecules. Roč. 11, č. 6 (2021), č. článku 791. E-ISSN 2218-273X
Institutional support: RVO:61388963
Keywords : GABA receptor * epipregnanolone * allopregnanolone * isopregnanolone * flumazenil patch clamp
OECD category: Neurosciences (including psychophysiology
Impact factor: 6.064, year: 2021
Method of publishing: Open access
https://doi.org/10.3390/biom11060791
Permanent Link: http://hdl.handle.net/11104/0320258 - 8.0541890 - FGÚ 2022 RIV CH eng J - Journal Article
Chvojková, Markéta - Kubová, Hana - Valeš, Karel
Effects of Dizocilpine, Midazolam and Their Co-Application on the Trimethyltin (TMT)-Induced Rat Model of Cognitive Deficit.
Brain Sciences. Roč. 11, č. 3 (2021), č. článku 400. E-ISSN 2076-3425
R&D Projects: GA ČR(CZ) GA18-09296S; GA ČR(CZ) GA14-20613S; GA MZd(CZ) NU20-04-00389; GA MZd(CZ) EF16_025/0007444
Institutional support: RVO:67985823
Keywords : cognitive function * trimethyltin * hippocampus * NMDA receptor * GABA A receptor * dementia * combination therapy * Alzheimer’s disease * neurodegeneration * neuroprotection
OECD category: Neurosciences (including psychophysiology
Impact factor: 3.333, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2076-3425/11/3/400
Permanent Link: http://hdl.handle.net/11104/0319385 - 9.0531146 - FGÚ 2021 RIV CH eng J - Journal Article
Kubová, Hana - Bendová, Z. - Moravcová, S. - Pačesová, D. - Rocha, L. - Mareš, Pavel
Neonatal Clonazepam Administration Induced Long-Lasting Changes in GABA(A) and GABA(B) Receptors.
International Journal of Molecular Sciences. Roč. 21, č. 9 (2020), č. článku 3184. E-ISSN 1422-0067
R&D Projects: GA ČR(CZ) GA19-11931S
Institutional support: RVO:67985823
Keywords : neonatal rat * clonazepam * GABA(A)/BZD receptor binding * GABA(B)receptor binding * subunit mRNA expression
OECD category: Neurosciences (including psychophysiology
Impact factor: 5.924, year: 2020
Method of publishing: Open access
https://www.mdpi.com/1422-0067/21/9/3184
Permanent Link: http://hdl.handle.net/11104/0309870 - 10.0524259 - FGÚ 2021 RIV US eng J - Journal Article
Vondráková, Kateřina - Novotný, P. - Kubová, Hana - Pošusta, Antonín - Boron, J. - Fáberová, Veronika - Fabene, P. F. - Burchfiel, J. - Tsenov, Grygoriy
Electrographic seizures induced by activation of ETA and ETB receptors following intrahippocampal infusion of endothelin-1 in immature rats occur by different mechanisms.
Experimental Neurology. Roč. 328, Jun (2020), č. článku 113255. ISSN 0014-4886. E-ISSN 1090-2430
R&D Projects: GA ČR(CZ) GA18-09296S; GA ČR(CZ) GA14-20613S
Institutional support: RVO:67985823
Keywords : ischemia * hippocampus * immature rat * endothelin * microdialysis, infmammatory * mass spektrometry * glutamate * GABA * leukotrienes * receptors * EEG * seizures
OECD category: Neurosciences (including psychophysiology
Impact factor: 5.330, year: 2020
Method of publishing: Limited access
https://doi.org/10.1016/j.expneurol.2020.113255
Permanent Link: http://hdl.handle.net/11104/0308641