Search results

  1. 1.
    0557244 - MBÚ 2023 RIV CH eng J - Journal Article
    Nekvasilová, Pavlína - Hovorková, Michaela - Mészáros, Zuzana - Petrásková, Lucie - Pelantová, Helena - Křen, Vladimír - Slámová, Kristýna - Bojarová, Pavla
    Engineered Glycosidases for the Synthesis of Analogs of Human Milk Oligosaccharides.
    International Journal of Molecular Sciences. Roč. 23, č. 8 (2022), č. článku 4106. E-ISSN 1422-0067
    R&D Projects: GA MŠMT(CZ) LTC20072; GA MŠMT(CZ) LTC19035; GA ČR(CZ) GA20-00215S
    EU Projects: European Commission(XE) CA18103
    Institutional support: RVO:61388971
    Keywords : beta-n-acetylhexosaminidase * crystal-structure * galactosidase * expression * lactose * cloning * glycosynthase * principle * gene * enzymatic synthesis * glycosidase * human milk oligosaccharide * mutagenesis
    OECD category: Biochemistry and molecular biology
    Impact factor: 5.6, year: 2022
    Method of publishing: Open access
    https://www.mdpi.com/1422-0067/23/8/4106
    Permanent Link: http://hdl.handle.net/11104/0331292
     
     
  2. 2.
    0509903 - ÚOCHB 2020 RIV US eng M - Monography Chapter
    Ménová, Petra - Cahová, Hana - Vrábel, Milan - Hocek, Michal
    Synthesis of Base-Modified dNTPs Through Cross-Coupling Reactions and Their Polymerase Incorporation to DNA.
    Non-Natural Nucleic Acids: Methods and Protocols. New York: Humana Press, 2019 - (Shank, N.), s. 39-57. Methods in Molecular Biology, 1973. ISBN 978-1-4939-9215-7
    R&D Projects: GA ČR(CZ) GA18-03305S; GA MŠMT(CZ) EF16_019/0000729
    Grant - others:AV ČR(CZ) AP1501
    Program: Akademická prémie - Praemium Academiae
    Institutional support: RVO:61388963
    Keywords : nucleotides * nucleoside triphosphates * DNA polymerases * enzymatic synthesis * modified DNA
    OECD category: Organic chemistry
    Permanent Link: http://hdl.handle.net/11104/0300492
     
     
  3. 3.
    0509795 - MBÚ 2020 RIV DE eng J - Journal Article
    Bojarová, Pavla - Bruthans, J. - Křen, Vladimír
    beta-N-Acetylhexosaminidases-the wizards of glycosylation.
    Applied Microbiology and Biotechnology. Roč. 103, č. 19 (2019), s. 7869-7881. ISSN 0175-7598. E-ISSN 1432-0614
    R&D Projects: GA MŠMT(CZ) LTC17005; GA MŠMT(CZ) LTC18041
    Institutional support: RVO:61388971
    Keywords : beta-N-acetylhexosaminidase * Carbohydrate * Enzymatic synthesis
    OECD category: Biochemistry and molecular biology
    Impact factor: 3.530, year: 2019
    Method of publishing: Limited access
    https://link.springer.com/article/10.1007%2Fs00253-019-10065-0
    Permanent Link: http://hdl.handle.net/11104/0300424
     
     
  4. 4.
    0498658 - ÚOCHB 2019 RIV US eng J - Journal Article
    Güixens-Gallardo, Pedro - Zawada, Zbigniew - Matyašovský, Ján - Dziuba, Dmytro - Pohl, Radek - Kraus, Tomáš - Hocek, Michal
    Brightly Fluorescent 2'-Deoxyribonucleoside Triphosphates Bearing Methylated Bodipy Fluorophore for in Cellulo Incorporation to DNA, Imaging, and Flow Cytometry.
    Bioconjugate Chemistry. Roč. 29, č. 11 (2018), s. 3906-3912. ISSN 1043-1802. E-ISSN 1520-4812
    R&D Projects: GA ČR GBP206/12/G151; GA ČR(CZ) GA17-14791S; GA MŠMT(CZ) EF16_019/0000729
    Grant - others:AV ČR(CZ) AP1501
    Program: Akademická prémie - Praemium Academiae
    Institutional support: RVO:61388963
    Keywords : nucleoside triphosphates * labeled nucleotides * enzymatic synthesis
    OECD category: Biochemistry and molecular biology
    Impact factor: 4.349, year: 2018
    Method of publishing: Open access
    https://pubs.acs.org/doi/10.1021/acs.bioconjchem.8b00721
    Permanent Link: http://hdl.handle.net/11104/0290953
    FileDownloadSizeCommentaryVersionAccess
    0498658.pdf46 MBPublisher’s postprintopen-access
     
     
  5. 5.
    0470348 - ÚOCHB 2017 RIV US eng J - Journal Article
    Slavíčková, Michaela - Pohl, Radek - Hocek, Michal
    Additions of Thiols to 7-Vinyl-7-deazaadenine Nucleosides and Nucleotides. Synthesis of Hydrophobic Derivatives of 2'-Deoxyadenosine, dATP and DNA.
    Journal of Organic Chemistry. Roč. 81, č. 22 (2016), s. 11115-11125. ISSN 0022-3263. E-ISSN 1520-6904
    R&D Projects: GA ČR GA14-04289S
    Institutional support: RVO:61388963
    Keywords : terminal deoxynucleotidyl transferase * enzymatic synthesis * cross linking
    Subject RIV: CC - Organic Chemistry
    Impact factor: 4.849, year: 2016
    http://pubs.acs.org/doi/abs/10.1021/acs.joc.6b02098
    Permanent Link: http://hdl.handle.net/11104/0268048
    FileDownloadSizeCommentaryVersionAccess
    0470348.pdf103.1 MBPublisher’s postprintopen-access
     
     
  6. 6.
    0469259 - ÚOCHB 2017 RIV US eng J - Journal Article
    Cahová, Hana - Panattoni, Alessandro - Kielkowski, Pavel - Fanfrlík, Jindřich - Hocek, Michal
    5-Substituted Pyrimidine and 7-Substituted 7-Deazapurine dNTPs as Substrates for DNA Polymerases in Competitive Primer Extension in the Presence of Natural dNTPs.
    ACS Chemical Biology. Roč. 11, č. 11 (2016), s. 3165-3171. ISSN 1554-8929. E-ISSN 1554-8937
    R&D Projects: GA ČR GA14-04289S
    EU Projects: European Commission(XE) 642023 - ClickGene
    Institutional support: RVO:61388963
    Keywords : enzymatic synthesis * 2'-deoxyribonucleoside triphosphates * restriction endonucleases
    OECD category: Biochemistry and molecular biology
    Impact factor: 4.995, year: 2016
    Method of publishing: Open access
    http://pubs.acs.org/doi/full/10.1021/acschembio.6b00714
    Permanent Link: http://hdl.handle.net/11104/0267059
    FileDownloadSizeCommentaryVersionAccess
    0469259.pdf32.7 MBPublisher’s postprintopen-access
     
     
  7. 7.
    0434401 - ÚMG 2015 RIV GB eng J - Journal Article
    Chlubnová, I. - Králová, B. - Dvořáková, H. - Hošek, P. - Spiwok, V. - Filipp, Dominik - Nugier-Chauvin, C. - Daniellou, R. - Ferrieres, V.
    The versatile enzyme Araf51 allowed efficient synthesis of rare pathogen-related beta-D-galactofuranosyl-pyranoside disaccharides.
    Organic & Biomolecular Chemistry. Roč. 12, č. 19 (2014), s. 3080-3089. ISSN 1477-0520. E-ISSN 1477-0539
    Grant - others:GA MŠk(CZ) LM2010005
    Institutional support: RVO:68378050
    Keywords : Galactofuranosyl-pyranoside dipeptides * Araf51 enzymatic synthesis * computer modelling
    Subject RIV: EB - Genetics ; Molecular Biology
    Impact factor: 3.562, year: 2014
    Permanent Link: http://hdl.handle.net/11104/0239754
     
     
  8. 8.
    0399041 - ÚOCHB 2014 US eng A - Abstract
    Krečmerová, Marcela - Blažek, Jiří - Andrei, G. - Balzarini, J. - Snoeck, R.
    New prodrugs of acyclic nucleoside analogues and phosphonomethyl derivatives.
    26th International Conference on Antiviral Research (ICAR). San Francisco: International Society for Antiviral Research (ISAR), 2013. s. 96-97.
    [International Conference on Antiviral Research /26./. 11.05.2013-15.05.2013, San Francisco]
    Grant - others:AV ČR(CZ) M200551201
    Institutional support: RVO:61388963
    Keywords : acyclic nucleoside phosphonate * antivirals * cytostatics * prodrug * enzymatic synthesis
    Subject RIV: CC - Organic Chemistry
    Permanent Link: http://hdl.handle.net/11104/0226444
     
     
  9. 9.
    0377791 - ÚOCHB 2013 RIV GB eng J - Journal Article
    Blažek, Jiří - Jansa, Petr - Baszczyňski, Ondřej - Kaiser, Martin Maxmilian - Otmar, Miroslav - Krečmerová, Marcela - Dračínský, Martin - Holý, Antonín - Králová, B.
    An enzymatic glycosylation of nucleoside analogues using beta-galactosidase from Escherichia coli.
    Bioorganic & Medicinal Chemistry. Roč. 20, č. 9 (2012), s. 3111-3118. ISSN 0968-0896. E-ISSN 1464-3391
    R&D Projects: GA MŠMT 1M0508
    Institutional research plan: CEZ:AV0Z40550506
    Keywords : glycosylation * galactosylation * beta-galactosidase * enzymatic synthesis * nucleoside * acyclic nucleoside analogues
    Subject RIV: CC - Organic Chemistry
    Impact factor: 2.903, year: 2012
    Permanent Link: http://hdl.handle.net/11104/0209855
     
     
  10. 10.
    0377487 - MBÚ 2013 RIV DE eng J - Journal Article
    Kupper, E. Ch. - Rosencrantz, R. R. - Henßen, B. - Pelantová, Helena - Thönes, S. - Drozdová, Anna - Křen, Vladimír - Elling, L.
    Chemo-enzymatic modification of poly-N-acetyllactosamine (LacNAc) oligomers and N,N-diacetyllactosamine (LacDiNAc) based on galactose oxidase treatment.
    Beilstein Journal of Organic Chemistry. Roč. 8, MAY 9 2012 (2012), s. 712-725. ISSN 1860-5397. E-ISSN 1860-5397
    R&D Projects: GA MŠMT OC09045
    Keywords : chemo-enzymatic synthesis * galactose oxidase * glycosyltransferase
    Subject RIV: CE - Biochemistry
    Impact factor: 2.801, year: 2012
    Permanent Link: http://hdl.handle.net/11104/0209632
     
     

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