Search results
- 1.0568233 - ÚOCHB 2024 RIV AT eng J - Journal Article
Makarov, A. - Began, Jakub - Mautone, I. C. - Pinto, E. - Ferguson, L. - Zoltner, M. - Zoll, Sebastian - Field, Mark Christian
The role of invariant surface glycoprotein 75 in xenobiotic acquisition by African trypanosomes.
Microbial cell. Roč. 10, č. 2 (2023), s. 18-35. E-ISSN 2311-2638
EU Projects: Wellcome Trust(GB) 204697/Z/16/Z
Research Infrastructure: CIISB II - 90127
Institutional support: RVO:61388963 ; RVO:60077344
Keywords : invariant surface glycoprotein * trypanosome * suramin * drug metabolism * drug accumulation * CRISPR/Cas9 * xenobiotics
OECD category: Biochemistry and molecular biology; Microbiology (BC-A)
Impact factor: 4.6, year: 2022
Method of publishing: Open access
https://doi.org/10.15698/mic2023.02.790
Permanent Link: https://hdl.handle.net/11104/0339563 - 2.0566038 - ARÚ 2023 RIV GB eng J - Journal Article
Mouterde, M. - Daali, Y. - Rollason, V. - Čížková, Martina - Mulugeta, A. - Al Balushi, K. A. - Fakis, G. - Constantinidis, T. C. - Al-Thihli, K. - Černá, M. - Makonnen, E. - Boukouvala, S. - Al-Yahyaee, S. - Yimer, G. - Černý, V. - Desmeules, J. - Poloni, E. S.
Joint analysis of phenotypic and genomic diversity sheds light on the evolution of xenobiotic metabolism in humans.
Genome Biology and Evolution. Roč. 14, č. 12 (2022), č. článku evac167. ISSN 1759-6653. E-ISSN 1759-6653
Grant - others:GA ČR(CZ) GA18-23889S
Institutional support: RVO:67985912
Keywords : ADME genes * drug metabolism phenotypes * genome-wide association studies * genome-wide selection scans * human evolution
OECD category: Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology
Impact factor: 3.3, year: 2022
Method of publishing: Open access
https://doi.org/10.1093/gbe/evac167
Permanent Link: https://hdl.handle.net/11104/0337480
Research data: Yareta - 3.0562994 - MBÚ 2023 RIV CH eng J - Journal Article
Šatka, Š. - Frýbortová, V. - Zapletalová, I. - Anzenbacher, P. - Anzenbacherová, E. - Kozáková, Hana - Šrůtková, Dagmar - Hudcovic, Tomáš - Jourová, L.
Effect of DSS-Induced Ulcerative Colitis and Butyrate on the Cytochrome P450 2A5: Contribution of the Microbiome.
International Journal of Molecular Sciences. Roč. 23, č. 19 (2022), č. článku 11627. E-ISSN 1422-0067
R&D Projects: GA ČR(CZ) GA19-08294S
Institutional support: RVO:61388971
Keywords : gut-liver axis * gut inflammation * butyrate * hepatic drug metabolism * cytochromes P450 * germ-free mice * microbiome
OECD category: Pharmacology and pharmacy
Impact factor: 5.6, year: 2022
Method of publishing: Open access
https://www.mdpi.com/1422-0067/23/19/11627
Permanent Link: https://hdl.handle.net/11104/0335224 - 4.0559852 - MBÚ 2023 RIV CH eng J - Journal Article
Jourová, L. - Satka, S. - Frýbortová, V. - Zapletalová, I. - Anzenbacher, P. - Anzenbacherová, E. - Hermanová, Petra - Draboňová, Barbora - Šrůtková, Dagmar - Kozáková, Hana - Hudcovic, Tomáš
Butyrate Treatment of DSS-Induced Ulcerative Colitis Affects the Hepatic Drug Metabolism in Mice.
Frontiers in Pharmacology. Roč. 13, JUL 19 2022 (2022), č. článku 936013. ISSN 1663-9812. E-ISSN 1663-9812
R&D Projects: GA ČR(CZ) GA19-08294S
Institutional support: RVO:61388971
Keywords : gut-liver axis * butyrate * gut inflammation * drug metabolism * cytochromes P450
OECD category: Pharmacology and pharmacy
Impact factor: 5.6, year: 2022
Method of publishing: Open access
https://www.frontiersin.org/articles/10.3389/fphar.2022.936013/full
Permanent Link: https://hdl.handle.net/11104/0333982 - 5.0541026 - ÚEB 2022 RIV CZ eng J - Journal Article
Spicakova, A. - Kraus, Petr - Gucký, Tomáš - Kryštof, Vladimír - Strnad, Miroslav - Bazgier, V. - Otyepka, M. - Kubickova, V. - Poruba, M. - Rácová, Z. - Zapletalová, I. - Anzenbacher, P.
in vitro and in silico Studies of Interaction of Synthetic 2,6,9-Trisubstituted Purine Kinase Inhibitors BPA-302, BP-21 and BP-117 With Liver Drug-Metabolizing Cytochromes P450.
Physiological Research. Roč. 69, SEP (2020), s. 627-636. ISSN 0862-8408. E-ISSN 1802-9973
R&D Projects: GA MZd(CZ) NV17-28231A
Institutional support: RVO:61389030
Keywords : r-roscovitine * cell-cycle * cancer * series * Cytochrome P450 inhibition * High performance liquid chromatography * Cyclin-dependent kinase inhibitor * FLT3-ITD inhibitor * Drug metabolism
OECD category: Organic chemistry
Impact factor: 1.881, year: 2020
Method of publishing: Open access
https://www.biomed.cas.cz/physiolres/pdf/2020/69_S627.pdf
Permanent Link: http://hdl.handle.net/11104/0318600File Download Size Commentary Version Access 2020_Spicakova_Physiological Research_S627.pdf 1 2.5 MB Other open-access - 6.0532671 - ÚEB 2021 RIV CH eng J - Journal Article
Raisová Stuchlíková, L. - Navrátilová, M. - Langhansová, Lenka - Moťková, Kateřina - Podlipná, Radka - Szotáková, B. - Skálová, L.
The identification of metabolites and effects of albendazole in alfalfa (Medicago sativa).
International Journal of Molecular Sciences. Roč. 21, č. 16 (2020), s. 1-12, č. článku 5943. E-ISSN 1422-0067
R&D Projects: GA ČR(CZ) GA18-07724S; GA MŠMT(CZ) EF16_019/0000738
Institutional support: RVO:61389030
Keywords : Anthelmintics * Drug metabolism * Drug phytotoxicity * Drugs in the environment * uhplc-ms/ms
OECD category: Pharmacology and pharmacy
Impact factor: 5.924, year: 2020
Method of publishing: Open access
http://doi.org/10.3390/ijms21165943
Permanent Link: http://hdl.handle.net/11104/0311128File Download Size Commentary Version Access 2020_Raisova-Stuchlikova_International Journal of Molecular Sciences_5943.pdf 2 375.4 KB Other open-access - 7.0496183 - ÚEB 2019 RIV US eng J - Journal Article
Landa, Přemysl - Přerostová, Sylva - Langhansová, Lenka - Maršík, Petr - Vaňková, Radomíra - Vaněk, Tomáš
Transcriptomic response of Arabidopsis thaliana roots to naproxen and praziquantel.
Ecotoxicology and Enviromental Safety. Roč. 166, DEC 30 (2018), s. 301-310. ISSN 0147-6513. E-ISSN 1090-2414
Grant - others:European Regional Development Fund(XE) CZ.02.1.01/0.0/0.0/ 16_019/0000738; OPPK(XE) CZ.2.16/3.1.00/21519
Institutional support: RVO:61389030
Keywords : personal care products * nonsteroidal antiinflammatory drugs * performance liquid-chromatography * tandem mass-spectrometry * glutathione transferases * pharmaceutical compounds * liver-microsomes * plant * water * detoxification * Pharmaceuticals * Microarrays * Gene expression * Pollution * Drug metabolism
OECD category: Plant sciences, botany
Impact factor: 4.527, year: 2018
Permanent Link: http://hdl.handle.net/11104/0289008File Download Size Commentary Version Access 2018_Landa_ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY_301.pdf 6 4.1 MB Other open-access - 8.0488847 - ÚEB 2019 RIV US eng J - Journal Article
Stuchlíková Raisová, L. - Skálová, L. - Szotáková, B. - Syslová, Eliška - Vokřál, I. - Vaněk, Tomáš - Podlipná, Radka
Biotransformation of flubendazole and fenbendazole and their effects in the ribwort plantain (Plantago lanceolata).
Ecotoxicology and Enviromental Safety. Roč. 147, JAN (2018), s. 681-687. ISSN 0147-6513. E-ISSN 1090-2414
R&D Projects: GA ČR(CZ) GA15-05325S
Institutional support: RVO:61389030
Keywords : Drug metabolism * Drug uptake * Fenbendazole * Flubendazole * Phytotoxicity * uhplc-ms/ms
OECD category: Biochemical research methods
Impact factor: 4.527, year: 2018
Permanent Link: http://hdl.handle.net/11104/0283369File Download Size Commentary Version Access 2018_Stuchlikova_ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY_681.pdf 1 982.4 KB Other open-access - 9.0487082 - ÚMG 2018 RIV US eng J - Journal Article
Sicho, M. - Kops, C.B. - Stork, C. - Svozil, Daniel - Kirchmair, J.
FAME 2: Simple and Effective Machine Learning Model of Cytochrome P450 Regioselectivity.
Journal of Chemical Information and Modeling. Roč. 57, č. 8 (2017), s. 1832-1846. ISSN 1549-9596. E-ISSN 1549-960X
R&D Projects: GA MŠMT LO1220; GA MŠMT LM2015063
Institutional support: RVO:68378050
Keywords : cyp-mediated sites * predicting drug-metabolism * xenobiotic metabolism * population analysis * pathway prediction * wave-functions * rs-predictor * p450 * reactivity * smartcyp
OECD category: Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)
Impact factor: 3.804, year: 2017
Permanent Link: http://hdl.handle.net/11104/0281766 - 10.0476524 - ÚEB 2018 RIV US eng J - Journal Article
Stuchlíková Raisová, L. - Podlipná, Radka - Szotáková, B. - Syslová, Eliška - Skálová, L.
Evaluation of drug uptake and deactivation in plant: Fate of albendazole in ribwort plantain (Plantago laceolata) cells and regenerants.
Ecotoxicology and Enviromental Safety. Roč. 141, JUL (2017), s. 37-42. ISSN 0147-6513. E-ISSN 1090-2414
R&D Projects: GA ČR(CZ) GA15-05325S
Institutional support: RVO:61389030
Keywords : Anthelmintics * Benzimidazoles * Drug metabolism * Drug uptake * Phytoremediation
OECD category: Bioremediation, diagnostic biotechnologies (DNA chips and biosensing devices) in environmental management
Impact factor: 3.974, year: 2017
Permanent Link: http://hdl.handle.net/11104/0273004File Download Size Commentary Version Access 2017_Stuchlikova-Raisova_ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY_37.pdf 2 801.3 KB Other open-access