Search results
- 1.0583492 - BFÚ 2024 RIV NL eng J - Journal Article
Sladekova, L. - Zgarbova, E. - Vrzal, R. - Vanda, D. - Soural, M. - Jakubcová, Klára - Vazquez-Gomez, Gerardo - Vondráček, Jan - Dvořák, Z.
Switching on/off aryl hydrocarbon receptor and pregnane X receptor activities by chemically modified tryptamines.
Toxicology Letters. Roč. 387, SEP 15 2023 (2023), s. 63-75. ISSN 0378-4274. E-ISSN 1879-3169
R&D Projects: GA ČR(CZ) GA22-00355S
Institutional support: RVO:68081707
Keywords : nuclear receptors * pxr * ahr * activation * antagonists * metabolism * tryptophan * ligands * target
OECD category: Toxicology
Impact factor: 3.5, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S037842742301055X?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0351455 - 2.0571976 - BFÚ 2024 RIV NL eng J - Journal Article
Marvanová, S. - Pěnčíková, K. - Palková, L. - Ciganek, M. - Petráš, Jiří - Lněničková, Anna - Vondráček, Jan - Machala, M.
Benzo[b]naphtho[d]thiophenes and naphthylbenzo[b]thiophenes: Their aryl hydrocarbon receptor-mediated activities and environmental presence.
Science of the Total Environment. Roč. 879, JUN 25 2023 (2023), č. článku 162924. ISSN 0048-9697. E-ISSN 1879-1026
R&D Projects: GA ČR(CZ) GA21-00533S
Institutional support: RVO:68081707
Keywords : Polycyclic aromatic sulfur heterocyclic * compounds * AhR activity * Gap junctional intercellular communication * Airborne particulate matter * Freshwater sediments
OECD category: Ecology
Impact factor: 9.8, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0048969723015401?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0349923 - 3.0561239 - ÚEM 2023 RIV CH eng J - Journal Article
Imran, S.J. - Vagaska, B. - Kriška, Ján - Anděrová, Miroslava - Bortolozzi, M. - Gerosa, G. - Ferretti, P. - Vrzal, R.
Aryl Hydrocarbon Receptor (AhR)-Mediated Signaling in iPSC-Derived Human Motor Neurons.
Pharmaceuticals. Roč. 15, č. 7 (2022), č. článku 828. E-ISSN 1424-8247
Institutional support: RVO:68378041
Keywords : AhR * CYP1A1 * KA * L-Kyn * hiPSCs * motor neurons * stem cell model
OECD category: Neurosciences (including psychophysiology
Impact factor: 4.6, year: 2022
Method of publishing: Open access
https://www.mdpi.com/1424-8247/15/7/828
Permanent Link: https://hdl.handle.net/11104/0333926 - 4.0561061 - BFÚ 2023 RIV CH eng J - Journal Article
Karasová, Martina - Procházková, Jiřina - Tylichová, Zuzana - Fedr, Radek - Ciganek, M. - Machala, M. - Dvořák, Z. - Vyhlidalova, B. - Zuvalova, I. - Ehrmann, J. - Bouchal, J. - Andrysík, Z. - Vondráček, Jan
Inhibition of Aryl Hydrocarbon Receptor (AhR) Expression Disrupts Cell Proliferation and Alters Energy Metabolism and Fatty Acid Synthesis in Colon Cancer Cells.
Cancers (Basel). Roč. 14, č. 17 (2022), č. článku 4245. E-ISSN 2072-6694
R&D Projects: GA ČR(CZ) GA19-00236S; GA MZd(CZ) NU21-03-00421
Institutional support: RVO:68081707
Keywords : colon cancer cells * AhR * metabolism * proliferation * fatty acid synthesis * Akt pathway
OECD category: Oncology
Impact factor: 5.2, year: 2022
Method of publishing: Open access
https://www.mdpi.com/2072-6694/14/17/4245
Permanent Link: https://hdl.handle.net/11104/0340614 - 5.0559979 - BC 2023 RIV NL eng J - Journal Article
Zhang, W. - Xie, H. Q. - Li, Y. - Zhou, Ming-Xi - Zhou, Z. - Wang, R. - Hahn, M. E. - Zhao, B.
The aryl hydrocarbon receptor: A predominant mediator for the toxicity of emerging dioxin-like compounds.
Journal of Hazardous Materials. Roč. 426, March 15 (2022), č. článku 128084. ISSN 0304-3894. E-ISSN 1873-3336
Institutional support: RVO:60077344
Keywords : Aryl hydrocarbon receptor * AHR ligands * Dioxin-like compounds * Molecular mechanisms * Toxicity evaluation
OECD category: Plant sciences, botany
Impact factor: 13.6, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0304389421030533?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0340342 - 6.0537447 - BFÚ 2021 RIV GB eng J - Journal Article
Vondráček, Jan - Pěnčíková, K. - Ciganek, M. - Pivnička, Jakub - Karasová, Martina - Hýžďalová, Martina - Strapáčová, S. - Palková, L. - Neca, J. - Matthews, J. - Vojtíšek-Lom, M. - Topinka, Jan - Milcová, Alena - Machala, M.
Environmental six-ring polycyclic aromatic hydrocarbons are potent inducers of the AhR-dependent signaling in human cells.
Environmental Pollution. Roč. 266, č. 2020 (2020), č. článku 115125. ISSN 0269-7491. E-ISSN 1873-6424
R&D Projects: GA ČR(CZ) GA16-17085S; GA MŠMT(CZ) LO1508
Institutional support: RVO:68081707 ; RVO:68378041
Keywords : standard reference materials * molecular-weight 302 * particulate matter * estrogen-receptor * urban dust * metabolic-activation * differential action * equivalency factors * AhR
OECD category: Cell biology; Cell biology (UEM-P)
Impact factor: 8.071, year: 2020
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0269749120326178?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0315184 - 7.0368757 - BFÚ 2012 RIV IE eng J - Journal Article
Hrubá, E. - Vondráček, Jan - Líbalová, Helena - Topinka, Jan - Bryja, Vítězslav - Souček, Karel - Machala, M.
Gene expression changes in human prostate carcinoma cells exposed to genotoxic and nongenotoxic aryl hydrocarbon receptor ligands.
Toxicology Letters. Roč. 206, č. 2 (2011), s. 178-188. ISSN 0378-4274. E-ISSN 1879-3169
R&D Projects: GA ČR(CZ) GA310/07/0961; GA ČR(CZ) GA524/09/1337
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702; CEZ:AV0Z50390512; CEZ:AV0Z50390703
Keywords : LNCaP cells * AhR ligands * WNT5A
Subject RIV: BO - Biophysics
Impact factor: 3.230, year: 2011
Permanent Link: http://hdl.handle.net/11104/0203013 - 8.0366424 - BFÚ 2012 RIV GB eng J - Journal Article
Procházková, Jiřina - Kabátková, Markéta - Bryja, Vítězslav - Umannová, Lenka - Bernatík, O. - Kozubík, Alois - Machala, M. - Vondráček, Jan
The interplay of the aryl hydrocarbon receptor and beta-catenin alters both AhR-dependent transcription and Wnt/beta-catenin signaling in liver progenitors.
Toxicological Sciences. Roč. 122, č. 2 (2011), s. 349-360. ISSN 1096-6080. E-ISSN 1096-0929
R&D Projects: GA ČR(CZ) GD204/09/H058
Grant - others:GA ČR(CZ) GA524/09/1337
Program: GA
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : dioxin * beta-catenin * AhR
Subject RIV: BO - Biophysics
Impact factor: 4.652, year: 2011
Permanent Link: http://hdl.handle.net/11104/0201426 - 9.0365816 - BFÚ 2012 RIV NL eng J - Journal Article
Andrysík, Zdeněk - Vondráček, Jan - Marvanová, S. - Ciganek, M. - Neča, J. - Pěnčíková, K. - Mahadevan, B. - Topinka, Jan - Baird, W.M. - Kozubík, Alois - Machala, M.
Activation of the aryl hydrocarbon receptor is the major toxic mode of action of an organic extract of a reference urban dust particulate matter mixture: The role of polycyclic aromatic hydrocarbons.
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. Roč. 714, 1-2 (2011), s. 53-62. ISSN 0027-5107
R&D Projects: GA ČR(CZ) GA310/07/0961
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702; CEZ:AV0Z50390512; CEZ:AV0Z50390703
Keywords : urban air pollution * PAHs * AhR
Subject RIV: BO - Biophysics
Impact factor: 2.850, year: 2011
Permanent Link: http://hdl.handle.net/11104/0200970 - 10.0359385 - BFÚ 2012 RIV NL eng J - Journal Article
Vondráček, Jan - Umannová, Lenka - Machala, M.
Interactions of the aryl hydrocarbon receptor with inflammatory mediators: Beyond CYP1A regulation.
Current Drug Metabolism. Roč. 12, č. 2 (2011), s. 89-103. ISSN 1389-2002. E-ISSN 1875-5453
R&D Projects: GA ČR(CZ) GAP503/11/1227
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : AhR * proinflammatory cytokines * antiinflammatory drugs
Subject RIV: BO - Biophysics
Impact factor: 5.113, year: 2011
Permanent Link: http://hdl.handle.net/11104/0197179