Acta chirurgiae orthopaedicae
et traumatologiae Čechoslovaca

Acta Chir Orthop Traumatol Cech. 2011; 78(1):49-55 | DOI: 10.55095/achot2011/008

Comparison of in Vivo Characteristics of Polyethylene Wear Particles Produced by a Metal and a Ceramic Femoral Component in Total Knee ReplacementOriginal papers

D. VEIGL¹, P. VAVŘÍK^1,*, D. POKORNݹ, M. ŠLOUF², E. PAVLOVA², I. LANDOR¹, P. Fulín¹

¹ I. ortopedická klinika 1. LF UK a FN Motol, Praha

² Ústav makromolekulární chemie AV ČR, Praha

PURPOSE OF THE STUDY:
The aim of the study was to evaluate in vivo and compare, in terms of the quality and number of ultra high-molecular polyethylene (UHMWPE) wear particles, total knee replacements of identical construction differing only in the material used for femoral component production, i.e., CoCrMo alloy or ZrO₂ ceramics.

MATERIAL AND METHODS:
Samples of peri-prosthetic granuloma tissue were collected in two patients with total knee replacement suffering from implant migration, who were matched in relevant characteristics. The primary knee replacement in Patient 1 with a CoCrMo femoral component was done 7.2 years and in Patient 2 with a ZrO₂ implant 6.8 years before this assessment. The polyethylene wear-induced granuloma was analysed by the MORF method enabling us to assess the shape and size of wear debris and the IRc method for assessment of particle concentration.

RESULTS:
In the granuloma tissue samples of Patient 1, on the average, particles were 0.30 mm in size and their relative volume was 0.19. In the Patient 2 tissue samples, the average size of particles was 0.33 mm and their relative volume was 0.26. There was no significant difference in either particle morphology or their concentration in the granuloma tissue between the two patients.

DISCUSSION:
One of the options of how to reduce the production of polyethylene wear particles is to improve the tribological properties of contacting surfaces in total knee replacement by substituting a cobalt-chrome femoral component with a zirconia ceramic femoral component. The previous in vitro testing carried out with a mechanical simulator under conditions approaching a real weight-bearing in the human body did show a nearly three-fold decrease in the number of UHMWPE wear particles in zirconia components. The evaluation of granuloma tissue induced by the activity of a real prosthetic joint for nearly seven years, however, did not reveal any great difference in either quality or quantity of polyethylene debris between the two replacements. The difference of surface roughness between CoCrMo (Ra = 0.05) and ZrO₂ (Ra = 0.02) components did not play any role in in vivo conditions.

CONCLUSIONS:
In accordance with a previous clinical study, this evaluation of the quality and quantity of UHMWPE wear particles produced by a ceramic femoral component in vivo failed to demonstrate any advantage of zirconia ceramic components over the cobalt-chrome femoral components so far used.

Keywords: total knee replacement, zirconia ceramic femoral component, comparative study, polyethylene wear, in vivo measurement

Published: February 1, 2011  Show citation