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Discovery of the first dual inhibitor of the 5-lipoxygenase-activating protein and soluble epoxide hydrolase using pharmacophore-based virtual screening

SYSNO	0474823
Title	Discovery of the first dual inhibitor of the 5-lipoxygenase-activating protein and soluble epoxide hydrolase using pharmacophore-based virtual screening
Author(s)	Temml, V. (AT) Garscha, U. (DE) Romp, E. (DE) Schubert, G. (DE) Gerstmeier, J. (DE) Kutil, Zsófia (UEB-Q) Matuszczak, B. (AT) Waltenberger, B. (AT) Stuppner, H. (AT) Werz, O. (DE) Schuster, D. (AT)
Corespondence/senior	Werz, O. - Korespondující autor Schuster, D. - Korespondující autor
Source Title	Scientific Reports. Roč. 7, FEB 20 (2017). - : Nature Publishing Group
Article number	42751
Document Type	Článek v odborném periodiku
Institutional support	UEB-Q - RVO:61389030
Language	eng
Country	GB
Keywords	activating protein * drug discovery * leukotriene biosynthesis * inflammatory diseases * conformer generation * arachidonic-acid * flap * challenges * asthma * risk
Permanent Link	http://hdl.handle.net/11104/0271773

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	2017_Temml_SCIENTIFIC REPORTS_42751.pdf	2	759.2 KB		Other	open-access

Number of the records: 1