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New Insights into Tolytoxin Effect in Human Cancer Cells: Apoptosis Induction and the Relevance of Hydroxyl Substitution of Its Macrolide Cycle on Compound Potency

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    SYSNO0553487
    TitleNew Insights into Tolytoxin Effect in Human Cancer Cells: Apoptosis Induction and the Relevance of Hydroxyl Substitution of Its Macrolide Cycle on Compound Potency
    Author(s) Delawská, Kateřina (MBU-M) ORCID
    Divoká, Petra (MBU-M)
    Sedlák, David (UMG-J) [38] RID
    Kuzma, Marek (MBU-M) ORCID, RID
    Saurav, Kumar (MBU-M) ORCID
    Macho, Markéta (MBU-M) ORCID
    Steinbach, G. (HU)
    Hrouzek, Pavel (MBU-M) ORCID
    Corespondence/seniorHrouzek, Pavel - Korespondující autor
    Source Title Chembiochem. Roč. 23, č. 1 (2022). - : Wiley
    Article numbere202100489
    Document TypeČlánek v odborném periodiku
    Grant GF21-05649K GA ČR - Czech Science Foundation (CSF), CZ - Czech Republic
    LO1416 GA MŠMT - Ministry of Education, Youth and Sports (MEYS), CZ - Czech Republic
    Interreg 41 Czech-Bavaria, XE - EU countries
    LM2018130 GA MŠMT - Ministry of Education, Youth and Sports (MEYS), CZ - Czech Republic
    Institutional supportMBU-M - RVO:61388971 ; UMG-J - RVO:68378050
    Languageeng
    CountryDE
    Keywords actin * binding * scytophycins * agents * actin disruption * apoptosis * cancer * scytophycines * tolytoxin
    Cooperating institutions Jihočeská univerzita České Budějovice (Czech Republic)
    URL https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/cbic.202100489
    Permanent Linkhttp://hdl.handle.net/11104/0330344
     
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