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Synthesis and Biological Evaluation of Phosphoester and Phosphorothioate Prodrugs of STING Agonist 3′,3′-c-Di(2′F,2′dAMP)

  1. 1.
    SYSNO0543611
    TitleSynthesis and Biological Evaluation of Phosphoester and Phosphorothioate Prodrugs of STING Agonist 3′,3′-c-Di(2′F,2′dAMP)
    Author(s) Pimková Polidarová, Markéta (UOCHB-X) [790/79] ORCID
    Břehová, Petra (UOCHB-X) [340/34] RID, ORCID
    Kaiser, Martin Maxmilian (UOCHB-X) [790/79] RID, ORCID
    Smola, Miroslav (UOCHB-X) [260/26] ORCID
    Dračínský, Martin (UOCHB-X) [910/91] RID, ORCID
    Smith, Joshua (UOCHB-X)
    Marek, Aleš (UOCHB-X) [960/96] RID, ORCID
    Dejmek, Milan (UOCHB-X) [350/35] RID, ORCID
    Šála, Michal (UOCHB-X) [350/35] RID, ORCID
    Gutten, Ondrej (UOCHB-X) [640/64] RID, ORCID
    Rulíšek, Lubomír (UOCHB-X) [640/64] RID, ORCID
    Novotná, Barbora (UOCHB-X) [790/79] ORCID
    Brázdová, Andrea (UOCHB-X) [790/79] ORCID
    Janeba, Zlatko (UOCHB-X) [340/34] RID, ORCID
    Nencka, Radim (UOCHB-X) [350/35] RID
    Bouřa, Evžen (UOCHB-X) [260/26] ORCID
    Páv, Ondřej (UOCHB-X) [790/79] RID, ORCID
    Birkuš, Gabriel (UOCHB-X) [790/79] ORCID
    Corespondence/seniorBirkuš, Gabriel - Korespondující autor
    Source Title Journal of Medicinal Chemistry. Roč. 64, č. 11 (2021), s. 7596-7616
    Document TypeČlánek v odborném periodiku
    Grant EF16_019/0000729 GA MŠk - Ministry of Education, Youth and Sports (MEYS), CZ - Czech Republic
    GA20-08772S GA ČR - Czech Science Foundation (CSF), CZ - Czech Republic
    Institutional supportUOCHB-X - RVO:61388963
    Languageeng
    CountryUS
    Keywords DNA sensor * interferon genes * cyclic GMP-AMP
    Cooperating institutions Univerzita Karlova (Czech Republic)
    URLhttps://doi.org/10.1021/acs.jmedchem.1c00301
    Permanent Linkhttp://hdl.handle.net/11104/0320799
     
Number of the records: 1