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Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine: Evaluation of a Novel Selective Inhibitor of Cyclin-Dependent Kinases with Antiproliferative Activity

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    SYSNO0368592
    TitlePyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine: Evaluation of a Novel Selective Inhibitor of Cyclin-Dependent Kinases with Antiproliferative Activity
    Author(s) Jorda, Radek (UEB-Q) ORCID, RID
    Havlíček, Libor (UEB-Q) RID, ORCID
    McNae, I. W. (GB)
    Walkinshaw, M. D. (GB)
    Voller, Jiří (UEB-Q) RID, ORCID
    Šturc, Antonín (UEB-Q)
    Navrátilová, Jana (UEB-Q)
    Kuzma, Marek (MBU-M) ORCID, RID
    Mistrik, M. (CZ)
    Bártek, J. (CZ)
    Strnad, Miroslav (UEB-Q) RID, ORCID
    Kryštof, Vladimír (UEB-Q) RID, ORCID
    Source Title Journal of Medicinal Chemistry. Roč. 54, č. 8 (2011), s. 2980-2993. - : American Chemical Society
    Document TypeČlánek v odborném periodiku
    Grant GA301/02/0475 GA ČR - Czech Science Foundation (CSF)
    GA301/08/1649 GA ČR - Czech Science Foundation (CSF)
    ED0007/01/01 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
    CEZAV0Z50380511 - UEB-Q (2005-2011)
    AV0Z50200510 - MBU-M (2005-2011)
    Languageeng
    CountryUS
    Keywords STRUCTURE-GUIDED DESIGN * DNA-END RESECTION * DOWN-REGULATION * R-ROSCOVITINE * CELL-CYCLE
    Permanent Linkhttp://hdl.handle.net/11104/0202891
    FileDownloadSizeCommentaryVersionAccess
    2011_Jorda_JOURNAL OF MEDICINAL CHEMISTRY_2980.pdf52.9 MBOtheropen-access
     
Number of the records: 1  

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