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There Is No Simple Model of the Plasma Membrane Organization

SYSNO ASEP	0463189
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	There Is No Simple Model of the Plasma Membrane Organization
Author(s)	de la Serna, J. B. (GB) Schütz, G. (AT) Eggeling, Ch. (GB) Cebecauer, Marek (UFCH-W)_{RID, ORCID, SAI}
Source Title	Frontiers in Cell and Developmental Biology. - : Frontiers Research Foundation - ISSN 2296-634X Roč. 4, SEP 2016 (2016), s. 106
Number of pages	17 s.
Language	eng - English
Country	CH - Switzerland
Keywords	plasma membrane ; membrane organization models ; heterogeneous distribution
Subject RIV	EA - Cell Biology
OECD category	Cell biology
R&D Projects	GA15-06989S GA ČR - Czech Science Foundation (CSF)
Institutional support	UFCH-W - RVO:61388955
UT WOS	000455229700106
EID SCOPUS	85018625624
DOI	10.3389/fcell.2016.00106
Annotation	Ever since technologies enabled the characterization of eukaryotic plasma membranes, heterogeneities in the distributions of its constituents were observed. Over the years this led to the proposal of various models describing the plasma membrane organization such as lipid shells, picket-and-fences, lipid rafts, or protein islands, as addressed in numerous publications and reviews. Instead of emphasizing on one model we in this review give a brief overview over current models and highlight how current experimental work in one or the other way do not support the existence of a single overarching model. Instead, we highlight the vast variety of membrane properties and components, their influences and impacts. We believe that highlighting such controversial discoveries will stimulate unbiased research on plasma membrane organization and functionality, leading to a better understanding of this essential cellular structure.
Workplace	J. Heyrovsky Institute of Physical Chemistry
Contact	Michaela Knapová, michaela.knapova@jh-inst.cas.cz, Tel.: 266 053 196
Year of Publishing	2017

Number of the records: 1