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Evolutionary ecology of aging: time to reconcile field and laboratory research

SYSNO ASEP	0458316
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Evolutionary ecology of aging: time to reconcile field and laboratory research
Author(s)	Reichard, Martin (UBO-W)_{RID, ORCID, SAI, SAI}
Number of authors	1
Source Title	Ecology and Evolution. - : Wiley - ISSN 2045-7758 Roč. 6, č. 9 (2016), s. 2988-3000
Number of pages	13 s.
Language	eng - English
Country	US - United States
Keywords	condition-dependence ; evolution of aging ; gene-by-environment interaction ; intrapopulation variability ; intraspecific aging rate ; mortality ; senescence
Subject RIV	EH - Ecology, Behaviour
OECD category	Ecology
R&D Projects	GA16-00291S GA ČR - Czech Science Foundation (CSF)
Institutional support	UBO-W - RVO:68081766
UT WOS	000376149400030
EID SCOPUS	84962177684
DOI	10.1002/ece3.2093
Annotation	Aging is an increase in mortality risk with age due to a decline in vital functions. Research on aging has entered an exciting phase. Advances in biogerontology have demonstrated that proximate mechanisms of aging and interventions to modify lifespan are shared among species. In nature, aging patterns have proven more diverse than previously assumed. The paradigm that extrinsic mortality ultimately determines evolution of aging rates has been questioned and there appears to be a mismatch between intra- and inter-specific patterns. The major challenges emerging in evolutionary ecology of aging are a lack of understanding of the complexity in functional senescence under natural conditions and unavailability of estimates of aging rates for matched populations exposed to natural and laboratory conditions. I argue that we need to reconcile laboratory and field-based approaches to better understand (1) how aging rates (baseline mortality and the rate of increase in mortality with age) vary across populations within a species, (2) how genetic and environmental variation interact to modulate individual expression of aging rates, and (3) how much intraspecific variation in lifespan is attributable to an intrinsic (i.e., nonenvironmental) component. I suggest integration of laboratory and field assays using multiple matched populations of the same species, along with measures of functional declines.
Workplace	Institute of Vertebrate Biology
Contact	Hana Slabáková, slabakova@ivb.cz, Tel.: 543 422 524
Year of Publishing	2019

Number of the records: 1