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Holocentromeres in Rhynchospora are associated with genome-wide centromere-specific repeat arrays interspersed among euchromatin

SYSNO ASEP	0450286
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Holocentromeres in Rhynchospora are associated with genome-wide centromere-specific repeat arrays interspersed among euchromatin
Author(s)	Marques, A. (DE) Ribeiro, T. (DE) Neumann, Pavel (BC-A)_{RID, ORCID} Macas, Jiří (BC-A)_{RID, ORCID, SAI} Novák, Petr (BC-A)_{RID, ORCID} Schubert, V. (DE) Pellino, M. (DE) Fuchs, J. (DE) Ma, W. (DE) Kuhlmann, M. (DE) Brandt, R. (DE) Vanzela, A.L.L. (BR) Beseda, Tomáš (UEB-Q)_RID Šimková, Hana (UEB-Q)_{RID, ORCID} Pedrosa-Harand, A. (DE) Houben, A. (DE)
Number of authors	16
Source Title	Proceedings of the National Academy of Sciences of the United States of America. - : National Academy of Sciences - ISSN 0027-8424 Roč. 112, č. 44 (2015), s. 13633-13638
Number of pages	6 s.
Publication form	Print - P
Language	eng - English
Country	US - United States
Keywords	Centromere ; satellite DNA ; holokinetic ; chromosome
Subject RIV	EB - Genetics ; Molecular Biology
Subject RIV - cooperation	Institute of Experimental Botany - Genetics ; Molecular Biology
R&D Projects	GBP501/12/G090 GA ČR - Czech Science Foundation (CSF)
	LO1204 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
Institutional support	BC-A - RVO:60077344 ; UEB-Q - RVO:61389030
UT WOS	000364164900067
DOI	10.1073/pnas.1512255112
Annotation	Holocentric chromosomes lack a primary constriction, in contrast to monocentrics. They form kinetochores distributed along almost the entire poleward surface of the chromatids, to which spindle fibers attach. No centromere-specific DNA sequence has been found for any holocentric organism studied so far. It was proposed that centromeric repeats, typical for many monocentric species, could not occur in holocentrics, most likely because of differences in the centromere organization. Here we show that the holokinetic centromeres of the Cyperaceae Rhynchospora pubera are highly enriched by a centromeric histone H3 variant-interacting centromere-specific satellite family designated “Tyba” and by centromeric retrotransposons (i.e., CRRh) occurring as genome-wide interspersed arrays. Centromeric arrays vary in length from 3 to 16 kb and are intermingled with gene-coding sequences and transposable elements.
Workplace	Biology Centre (since 2006)
Contact	Dana Hypšová, eje@eje.cz, Tel.: 387 775 214
Year of Publishing	2016

Number of the records: 1