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An Intrinsic MicroRNA Timer Regulates Progressive Decline in Shoot Regenerative Capacity in Plants
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SYSNO ASEP 0446312 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title An Intrinsic MicroRNA Timer Regulates Progressive Decline in Shoot Regenerative Capacity in Plants Author(s) Zhang, T.Q. (CN)
Lian, H. (CN)
Tang, H.B. (CN)
Doležal, Karel (UEB-Q) RID, ORCID
Zhou, E.M. (CN)
Yu, S. (CN)
Chen, J.H. (CN)
Chen, Q. (CN)
Liu, H.T. (CN)
Ljung, K.R. (CN)
Wang, J.W. (CN)Source Title Plant Cell. - : Oxford University Press - ISSN 1040-4651
Roč. 27, č. 2 (2015), s. 349-360Number of pages 12 s. Language eng - English Country US - United States Keywords CYTOKININ SIGNAL-TRANSDUCTION ; B RESPONSE REGULATORS ; ARABIDOPSIS-THALIANA Subject RIV EB - Genetics ; Molecular Biology R&D Projects LO1204 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) Institutional support UEB-Q - RVO:61389030 UT WOS 000350765300005 DOI 10.1105/tpc.114.135186 Annotation Plant cells are totipotent and competent to regenerate from differentiated organs. It has been shown that two phytohormones, auxin and cytokinin, play critical roles within this process. As in animals, the regenerative capacity declines with age in plants, but the molecular basis for this phenomenon remains elusive. Here, we demonstrate that an age-regulated microRNA, miR156, regulates shoot regenerative capacity. As a plant ages, the gradual increase in miR156-targeted SQUAMOSA PROMOTER BINDING PROTEIN-LIKE (SPL) transcription factors leads to the progressive decline in shoot regenerative capacity. In old plants, SPL reduces shoot regenerative capacity by attenuating the cytokinin response through binding with the B-type ARABIDOPSIS RESPONSE REGULATORs, which encode the transcriptional activators in the cytokinin signaling pathway. Consistently, the increased amount of exogenous cytokinin complements the reduced shoot regenerative capacity in old plants. Therefore, the recruitment of age cues in response to cytokinin contributes to shoot regenerative competence. Workplace Institute of Experimental Botany Contact David Klier, knihovna@ueb.cas.cz, Tel.: 220 390 469 Year of Publishing 2016
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