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Humans and great apes cohabiting the forest ecosystem in Central African Republic harbour the same hookworms
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SYSNO ASEP 0427111 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Humans and great apes cohabiting the forest ecosystem in Central African Republic harbour the same hookworms Author(s) Hasegawa, H. (JP)
Modrý, D. (CZ)
Kitagawa, M. (JP)
Shutt, K. A. (GB)
Todd, A. (CF)
Kalousová, B. (CZ)
Profousová, I. (CZ)
Petrželková, Klára Judita (UBO-W) RID, SAI, ORCIDNumber of authors 8 Source Title PLoS Neglected Tropical Diseases. - : Public Library of Science - ISSN 1935-2727
Roč. 8, č. 3 (2014), e2715Number of pages 10 s. Language eng - English Country US - United States Keywords Necator spp. ; mountain gorillas ; infection ; chimpanzees ; Dzanga-Sangha Protected Areas, Central African Republic Subject RIV EG - Zoology R&D Projects GA206/09/0927 GA ČR - Czech Science Foundation (CSF) Institutional support UBO-W - RVO:68081766 UT WOS 000337348800007 EID SCOPUS 84897461139 DOI https://doi.org/10.1371/journal.pntd.0002715 Annotation We conducted analyses of DNA sequences obtained from the infective larvae of Necator spp. from humans and great apes inhabiting Dzanga-Sangha Protected Areas, Central African Republic. Three sequence types (I–III) were recognized in the in the ITS region, and 34 cox1 haplotypes represented three phylogenetic groups (A–C). I-A, II-B, II-C, III-B, III-C combinations were determined. Combination I-A, corresponding to Necator americanus, was demonstrated in humans and western lowland gorillas; II-B and II-C were observed in humans (local inhabitants and researchers), western lowland gorillas and chimpanzees; III-B and III-C were found only in humans. Pairwise nucleotide difference in the cox1 haplotypes between the groups was more than 8%, while the difference within each group was less than 2.1%, suggesting that each type represents a distinct species. This is the first molecular evidence that Necator species found in great apes can infect humans and vice versa. Workplace Institute of Vertebrate Biology Contact Hana Slabáková, slabakova@ivb.cz, Tel.: 543 422 524 Year of Publishing 2015
Number of the records: 1