Humans and great apes cohabiting the forest ecosystem in Central African Republic harbour the same hookworms

Hasegawa, H.; Modrý, D.; Kitagawa, M.; Shutt, K. A.; Todd, A.; Kalousová, B.; Profousová, I.; Petrželková, Klára Judita

doi:https://dx.doi.org/10.1371/journal.pntd.0002715

Number of the records: 1

Humans and great apes cohabiting the forest ecosystem in Central African Republic harbour the same hookworms

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SYSNO ASEP	0427111
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Humans and great apes cohabiting the forest ecosystem in Central African Republic harbour the same hookworms
Author(s)	Hasegawa, H. (JP) Modrý, D. (CZ) Kitagawa, M. (JP) Shutt, K. A. (GB) Todd, A. (CF) Kalousová, B. (CZ) Profousová, I. (CZ) Petrželková, Klára Judita (UBO-W)_{RID, SAI, ORCID}
Number of authors	8
Source Title	PLoS Neglected Tropical Diseases. - : Public Library of Science - ISSN 1935-2735 Roč. 8, č. 3 (2014), e2715
Number of pages	10 s.
Language	eng - English
Country	US - United States
Keywords	Necator spp. ; mountain gorillas ; infection ; chimpanzees ; Dzanga-Sangha Protected Areas, Central African Republic
Subject RIV	EG - Zoology
R&D Projects	GA206/09/0927 GA ČR - Czech Science Foundation (CSF)
Institutional support	UBO-W - RVO:68081766
UT WOS	000337348800007
EID SCOPUS	84897461139
DOI	10.1371/journal.pntd.0002715
Annotation	We conducted analyses of DNA sequences obtained from the infective larvae of Necator spp. from humans and great apes inhabiting Dzanga-Sangha Protected Areas, Central African Republic. Three sequence types (I–III) were recognized in the in the ITS region, and 34 cox1 haplotypes represented three phylogenetic groups (A–C). I-A, II-B, II-C, III-B, III-C combinations were determined. Combination I-A, corresponding to Necator americanus, was demonstrated in humans and western lowland gorillas; II-B and II-C were observed in humans (local inhabitants and researchers), western lowland gorillas and chimpanzees; III-B and III-C were found only in humans. Pairwise nucleotide difference in the cox1 haplotypes between the groups was more than 8%, while the difference within each group was less than 2.1%, suggesting that each type represents a distinct species. This is the first molecular evidence that Necator species found in great apes can infect humans and vice versa.
Workplace	Institute of Vertebrate Biology
Contact	Hana Slabáková, slabakova@ivb.cz, Tel.: 543 422 524
Year of Publishing	2015

Number of the records: 1