Number of the records: 1
HPV16-associated tumours: Therapy of surgical minimal residual disease with dendritic cell-based vaccines
- 1.
SYSNO ASEP 0105308 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Ostatní články Title HPV16-associated tumours: Therapy of surgical minimal residual disease with dendritic cell-based vaccines Title Léčba chirurgické minimální zbytkové choroby pomocí vakcín dendritických buněk Author(s) Reiniš, Milan (UMG-J) RID
Indrová, Marie (UMG-J) RID
Mendoza, Luis (UMG-J)
Mikyšková, Romana (UMG-J) RID
Bieblová, Jana (UMG-J)
Bubeník, Jan (UMG-J)
Šímová, Jana (UMG-J) RIDSource Title International Journal of Oncology. - : Spandidos Publications - ISSN 1019-6439
Roč. 25, č. 4 (2004), s. 1165-1170Number of pages 6 s. Language eng - English Country GR - Greece Keywords HPV16 ; minimal residual tumour disease ; dendritic cells Subject RIV EC - Immunology R&D Projects NC7148 GA MZd - Ministry of Health (MZ) GA301/04/0492 GA ČR - Czech Science Foundation (CSF) GA301/01/0985 GA ČR - Czech Science Foundation (CSF) IAA5052203 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) CEZ AV0Z5052915 - UMG-J Annotation Dendritic cell (DC)-based vaccines are being intensively studied for the treatment of a variety of human neoplasms. However, little attention has been paid to the use of these vaccines for immunotherapy of tumour residua after surgery. In this communication, an animal model mimicking human HPV16-associated neoplasms was employed to examine the effect of DC-based vaccines for the treatment of surgical minimal residual tumour disease. A positive effect of local administration of the DC-based, HPV16 E6/E7 oncoprotein-containing, tumour lysate-loaded vaccines was observed Workplace Institute of Molecular Genetics Contact Nikol Škňouřilová, nikol.sknourilova@img.cas.cz, Tel.: 241 063 217 Year of Publishing 2005
Number of the records: 1