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Additive transport in DNA molecular circuits
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SYSNO ASEP 0563907 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Additive transport in DNA molecular circuits Author(s) Sebechlebská, T. (SK)
Kolivoška, V. (CZ)
Šebera, Jakub (UOCHB-X) RID, ORCID
Fukal, Jiří (UOCHB-X) ORCID, RID
Řeha, D. (CZ)
Buděšínský, Miloš (UOCHB-X) RID, ORCID
Rosenberg, Ivan (UOCHB-X) RID, ORCID
Bednárová, Lucie (UOCHB-X) RID, ORCID
Gasior, J. (CZ)
Mészáros, G. (HU)
Hromadová, M. (CZ)
Sychrovský, Vladimír (UOCHB-X) RID, ORCIDSource Title Journal of Materials Chemistry C. - : Royal Society of Chemistry - ISSN 2050-7526
Roč. 10, č. 33 (2022), s. 12022-12031Number of pages 10 s. Language eng - English Country GB - United Kingdom Keywords photoinduced electron-transfer ; HG-II-T ; charge-transport OECD category Biophysics R&D Projects GA18-14990S GA ČR - Czech Science Foundation (CSF) Method of publishing Open access Institutional support UOCHB-X - RVO:61388963 UT WOS 000837444200001 EID SCOPUS 85135723962 DOI 10.1039/d2tc01219g Annotation This work describes additive transport in DNA molecules due to a self-assembly of complementary single-stranded deoxyribonucleic acid chains, i.e. DNA hybridization. Charge transport properties in the DNA junctions at the single molecule level were studied experimentally by the break junction technique in an aqueous environment and theoretically including a non-equilibrium Green's function approach within the density functional based tight-binding method and molecular orbital calculations using density functional method and molecular dynamics simulations. Two types of anchoring groups, namely, amino and thiolate moieties were used to connect the single-stranded DNA (anchor-linker-3'-GGCACTCGG-5'-linker-anchor) to gold electrodes. Double-stranded DNA junctions were prepared by hybridization of single-stranded DNA with a complementary oligonucleotide chain (5'-CCGTGAGCC-3') not containing linkers and anchoring groups. Three stable junction configurations were observed for both single-stranded and double-stranded DNA irrespective of the anchoring group, whereas junction conductance almost doubled upon DNA hybridization. Thiolate anchoring led to more robust and longer junction configurations compared to NH2 groups. Reasons for the observed conductance enhancement and the anchoring group effect on the overall conductance are being discussed. Workplace Institute of Organic Chemistry and Biochemistry Contact asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Viktorie Chládková, Tel.: 232 002 434 Year of Publishing 2023 Electronic address https://doi.org/10.1039/D2TC01219G
Number of the records: 1