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Hybrid coatings for orthopaedic implants formed by physical vapour deposition and microarc oxidation

SYSNO ASEP	0560431
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Hybrid coatings for orthopaedic implants formed by physical vapour deposition and microarc oxidation
Author(s)	Gabor, R. (CZ) Cvrček, L. (CZ) Doubková, Martina (FGU-C)_{ORCID, RID} Nehasil, V. (CZ) Hlinka, J. (CZ) Unucka, P. (CZ) Buřil, M. (CZ) Podepřelová, A. (CZ) Seidlerová, J. (CZ) Bačáková, Lucie (FGU-C)_{RID, ORCID}
Article number	110811
Source Title	Materials and Design. - : Elsevier - ISSN 0264-1275 Roč. 219, July (2022)
Number of pages	17 s.
Language	eng - English
Country	GB - United Kingdom
Keywords	Ti-6Al-4V ; PVD coating ; MAO process ; corrosion protection ; tribology ; mesenchymal stem cells
OECD category	Biomaterials (as related to medical implants, devices, sensors)
R&D Projects	GA20-01570S GA ČR - Czech Science Foundation (CSF)
Method of publishing	Open access
Institutional support	FGU-C - RVO:67985823
UT WOS	000880130400004
EID SCOPUS	85131463121
DOI	10.1016/j.matdes.2022.110811
Annotation	This study is focused on the preparation of new hybrid layers intended for surface modification of Ti-6Al-4V alloys for potential orthopaedic and dental applications. Combination of the technology of physical vapour deposition (PVD) and subsequent micro-arc oxidation (MAO) was utilized for the deposition of Ti and ZrTi to form hybrid oxide layers. The oxide layers were prepared using an alkaline electrolyte with glycerol as an additive under micro-arc discharge conditions with different Si content on their surfaces. The hybrid ZrTi coatings with a Zr/Si structure achieved the best tribological properties described by a low friction coefficient of 0.3 and high abrasion resistance. There was also an increase in corrosion potential and polarization resistance of hybrid ZrTi coatings. Although the proliferation of human bone marrow mesenchymal stem cells was slower on these hydrophilic Ti and ZrTi coatings than both on uncoated Ti-6Al-4V and the reference tissue culture polystyrene dishes, both types of hybrid coating promoted greater osteogenic differentiation of these cells, indicated by approx. twice as high activity of alkaline phosphatase. The hybrid oxide layers newly developed in this study – especially the layers with Zr – are therefore promising for coating metallic bone implants.
Workplace	Institute of Physiology
Contact	Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400
Year of Publishing	2023
Electronic address	https://doi.org/10.1016/j.matdes.2022.110811

Number of the records: 1