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Fiber optic probe with antifouling polymer brush biointerface for bi- modal biosensing in complex liquid samples
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SYSNO ASEP 0559043 Document Type C - Proceedings Paper (int. conf.) R&D Document Type Conference Paper Title Fiber optic probe with antifouling polymer brush biointerface for bi- modal biosensing in complex liquid samples Author(s) Hasler, R. (AT)
Víšová, Ivana (FZU-D) ORCID
Vrabcová, Markéta (FZU-D) ORCID
Houska, Milan (FZU-D) ORCID
Spasovová, Monika (FZU-D) ORCID
Vaisocherová-Lísalová, Hana (FZU-D) ORCID
Dostálek, Jakub (FZU-D) ORCIDNumber of authors 7 Article number 1214505 Source Title Proceedings of SPIE. - Bellingham : SPIE, 2022 / Canva M.T. ; Giannetti A. ; Altug H. ; Moreau J. - ISSN 0277-786X Number of pages 9 s. Publication form Online - E Action SPIE Photonics Europe 2022 Event date 03.04.2022 - 23.05.2022 VEvent location Strasbourg Country FR - France Event type EUR Language eng - English Country US - United States Keywords surface plasmon resonance ; field effect transistor ; cyclic voltammetry ; biosensor ; antifouling polymer brush Subject RIV BO - Biophysics OECD category Biophysics R&D Projects GA21-19779S GA ČR - Czech Science Foundation (CSF) GC22-30456J GA ČR - Czech Science Foundation (CSF) Institutional support FZU-D - RVO:68378271 UT WOS 000844428800004 EID SCOPUS 85134383165 DOI 10.1117/12.2621192 Annotation We report on the utilization of an antifouling brush biointerface at the surface of surface plasmon resonance (SPR) optical probe for real-world biosensor applications. This biointerface architecture provides the advantage of resistance to fouling when contacted with complex biological fluids, it can be postmodified with functional biomolecular species for affinity biosensor applications, and allows for combined optical and electronic-based biosensing. The SPR optical probe carrying the thin gold film and antifouling polymer brush architecture is successfully implemented as a gate electrode in electrolyte-gated field effect transistor (EG-FET) readout and as a working electrode in cyclic voltammetry (CV). The poly(carboxybetaine acrylamide) (pCBAA) brush was synthesized by the ‘grafting from’ approach with a thickness matching the evanescent field of surface plasmons. Workplace Institute of Physics Contact Kristina Potocká, potocka@fzu.cz, Tel.: 220 318 579 Year of Publishing 2023 Electronic address https://www.spiedigitallibrary.org/conference-proceedings-of-spie/12145/2621192/Fiber-optic-probe-with-antifouling-polymer-brush-biointerface-for-bi/10.1117/12.2621192.short?SSO=1
Number of the records: 1