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Variability and Randomness of the Instantaneous Firing Rate

SYSNO ASEP	0543840
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Variability and Randomness of the Instantaneous Firing Rate
Author(s)	Tomar, Rimjhim (FGU-C)_ORCID Košťál, Lubomír (FGU-C)_{RID, ORCID, SAI}
Article number	620410
Source Title	Frontiers in Computational Neuroscience. - : Frontiers Media Roč. 15, Jun 7 (2021)
Number of pages	12 s.
Language	eng - English
Country	CH - Switzerland
Keywords	variability ; randomness ; firing rate ; entropy ; rate coding ; neural coding ; temporal coding ; instantaneous firing rate
Subject RIV	BB - Applied Statistics, Operational Research
OECD category	Statistics and probability
R&D Projects	GA20-10251S GA ČR - Czech Science Foundation (CSF)
Method of publishing	Open access
Institutional support	FGU-C - RVO:67985823
UT WOS	000663635200001
EID SCOPUS	85108383814
DOI	10.3389/fncom.2021.620410
Annotation	The apparent stochastic nature of neuronal activity significantly affects the reliability of neuronal coding. To quantify the encountered fluctuations, both in neural data and simulations, the notions of variability and randomness of inter-spike intervals have been proposed and studied. In this article we focus on the concept of the instantaneous firing rate, which is also based on the spike timing. We use several classical statistical models of neuronal activity and we study the corresponding probability distributions of the instantaneous firing rate. To characterize the firing rate variability and randomness under different spiking regimes, we use different indices of statistical dispersion. We find that the relationship between the variability of interspike intervals and the instantaneous firing rate is not straightforward in general. Counter-intuitively, an increase in the randomness (based on entropy) of spike times may either decrease or increase the randomness of instantaneous firing rate, in dependence on the neuronal firing model. Finally, we apply our methods to experimental data, establishing that instantaneous rate analysis can indeed provide additional information about the spiking activity.
Workplace	Institute of Physiology
Contact	Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400
Year of Publishing	2022
Electronic address	https://doi.org/10.3389/fncom.2021.620410

Number of the records: 1