Number of the records: 1
Chiral detection by induced surface-enhanced Raman optical activity
- 1.
SYSNO ASEP 0543207 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Chiral detection by induced surface-enhanced Raman optical activity Author(s) Das, Moumita (UOCHB-X) ORCID
Gangopadhyay, Debraj (UOCHB-X) ORCID
Šebestík, Jaroslav (UOCHB-X) RID, ORCID
Habartová, L. (CZ)
Michal, P. (CZ)
Kapitán, J. (CZ)
Bouř, Petr (UOCHB-X) RID, ORCIDSource Title Chemical Communications. - : Royal Society of Chemistry - ISSN 1359-7345
Roč. 57, č. 52 (2021), s. 6388-6391Number of pages 4 s. Language eng - English Country GB - United Kingdom Keywords vibrational circular-dichroism ; molecules ; scattering OECD category Physical chemistry R&D Projects EF16_019/0000729 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) GA20-10144S GA ČR - Czech Science Foundation (CSF) Method of publishing Open access Institutional support UOCHB-X - RVO:61388963 UT WOS 000657663200001 EID SCOPUS 85108877040 DOI https://doi.org/10.1039/d1cc01504d Annotation Combination of optical activity with surface-enhanced Raman scattering has been a dream of physical chemists for a long time. We report a measurement protocol based on silver colloids and aromatic linkers where chiral acids could be detected in concentrations of about 10−5 M. We explain the mechanism by binding and self-assembly of the linkers into chiral aggregates on the silver surface. Following the “sergeants-and-soldiers” principle, the chirality is determined by the relatively minor acidic component. Such detection of biologically relevant molecules may be useful when other methods, such as electronic circular dichroism, are not sensitive enough. In the future, variations of the chemical structure of the linker or other conditions are needed to provide a more specific signal allowing one to better discriminate among the optically active molecules. Workplace Institute of Organic Chemistry and Biochemistry Contact asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Jana Procházková, Tel.: 220 183 418 Year of Publishing 2022 Electronic address https://doi.org/10.1039/D1CC01504D
Number of the records: 1