Number of the records: 1
Self-assembly of bovine serum albumin (BSA)-dextran bio-nanoconjugate: structural, antioxidant and in vitro wound healing studies
- 1.
SYSNO ASEP 0541280 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Self-assembly of bovine serum albumin (BSA)-dextran bio-nanoconjugate: structural, antioxidant and in vitro wound healing studies Author(s) Rohiwal, Sonali Suresh (UZFG-Y) ORCID
Ellederová, Zdeňka (UZFG-Y) RID, ORCID
Tiwari, A. P. (IN)
Alqarni, M. (SA)
Elazab, S. T. (EG)
El-Saber Batiha, G. (EG)
Pawar, S. H. (IN)
Thorat, N. D. (GB)Source Title RSC Advances. - : Royal Society of Chemistry
Roč. 11, č. 8 (2021), s. 4308-4317Number of pages 10 s. Publication form Print - P Language eng - English Country GB - United Kingdom Keywords bovine serum albumin ; dextran ; wound healing Subject RIV EB - Genetics ; Molecular Biology OECD category Biochemistry and molecular biology R&D Projects LO1609 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) Method of publishing Open access Institutional support UZFG-Y - RVO:67985904 UT WOS 000612191100003 EID SCOPUS 85100012065 DOI 10.1039/d0ra09301g Annotation Glycation of proteins is often considered as a method to improve their functional properties for promising applications in wound healing. Furthermore, a marked increase in percentage of radical scavenging activity of the conjugates makes it an effective antioxidant synthetic strategy. A simple conjugation process was employed to develop bovine serum albumin-dextran conjugates (BSA-dextran) using Maillard reaction. Higher electrophoretic mobility and surface charge in the prepared conjugates was observed in native PAGE electrophoresis and zeta potential. Moreover, the fluorescence, FTIR and Raman analysis of the BSA-dextran conjugates shows significant shift in the fluorescence and wavelength as a consequence of conjugate formation. In vitro wound healing assay showed increased cell proliferation and migration effect. These finding suggests that BSA-dextran conjugate could open up a new practical way for exploration in the area of wound healing. Workplace Institute of Animal Physiology and Genetics Contact Jana Zásmětová, knihovna@iapg.cas.cz, Tel.: 315 639 554 Year of Publishing 2022 Electronic address https://pubs.rsc.org/en/content/articlelanding/ra/2021/d0ra09301g#!divAbstract
Number of the records: 1