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Nafion membranes modified by cationic cyclodextrin derivatives for enantioselective separation.

SYSNO ASEP	0540919
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Nafion membranes modified by cationic cyclodextrin derivatives for enantioselective separation.
Author(s)	Gaálová, Jana (UCHP-M)_{RID, SAI, ORCID} Michel, Marine (UCHP-M) Bourassi, Mahdi (UCHP-M)_{ORCID, RID, SAI} Ladewing, B.P. (GB) Kasal, P. (CZ) Jindřich, J. (CZ) Izák, Pavel (UCHP-M)_{RID, ORCID, SAI}
Article number	118538
Source Title	Separation and Purification Technology. - : Elsevier - ISSN 1383-5866 Roč. 266, Jul 1 (2021)
Number of pages	10 s.
Language	eng - English
Country	GB - United Kingdom
Keywords	nafion membranes ; cyclodextrin derivatives ; strong ionic binding
Subject RIV	CI - Industrial Chemistry, Chemical Engineering
OECD category	Chemical process engineering
R&D Projects	GA20-09980S GA ČR - Czech Science Foundation (CSF)
	GJ19-08153Y GA ČR - Czech Science Foundation (CSF)
	FV10082 GA MPO - Ministry of Industry and Trade (MPO)
Method of publishing	Open access with time embargo (02.07.2023)
Institutional support	UCHP-M - RVO:67985858
UT WOS	000647567000006
EID SCOPUS	85102647289
DOI	10.1016/j.seppur.2021.118538
Annotation	Nafion117® membranes modified by three cationic cyclodextrin (CD) derivatives have been prepared by strong ionic bonding. All CD derivatives contained bis(methylimidazolium) (MIM2) cationic anchor covalently bound to the CD unit, either using no spacer or using diethylene glycol (DEG) or tetraethylene glycol (TEEG) spacers. The modified membranes were tested in chiral separation of a model racemic mixture (d/l-tryptophan) from water. Different experimental set-ups for characterising membranes in enantioselective separation – pertraction, two kinds of sorption, and pressure-driven membrane separation – have been described and rigorously compared. The membranes CD-MIM2, CD-DEG-MIM2 have reached the highest enantiomeric excess, 14 and 44% respectively, in 280 days. The lowest performance of the CD-TEEG-MIM2 membrane, with the long spacer, has been visibly ameliorated by applying pertraction, enantiomeric excess rose from 2 to 27% in 80 days. Even though sorption played the main role in pertraction, this process substantially enhanced the separation of racemic mixtures. The pressure-driven approach has allowed the operation to be continuous and faster, which has the potential for continuous large-scale production of enantiopure compounds and could pave the way for many more commercial applications, satisfying the considerable demand for large-scale chiral separation techniques.
Workplace	Institute of Chemical Process Fundamentals
Contact	Eva Jirsová, jirsova@icpf.cas.cz, Tel.: 220 390 227
Year of Publishing	2022
Electronic address	http://hdl.handle.net/11104/0318604

Number of the records: 1