Number of the records: 1
Effect of Polycyclic Aromatic Hydrocarbons Exposure on Cognitive Development in 5 Years Old Children
- 1.
SYSNO ASEP 0539320 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Effect of Polycyclic Aromatic Hydrocarbons Exposure on Cognitive Development in 5 Years Old Children Author(s) Blažková, B. (CZ)
Pastorková, Anna (UEM-P) RID
Solanský, I. (CZ)
Veleminský Jr., M. (CZ)
Veleminský, M. (CZ)
Urbancová, K. (CZ)
Vondrašková, V. (CZ)
Hajslová, J. (CZ)
Pulkrabová, J. (CZ)
Šrám, Radim (UEM-P) RIDArticle number 619 Source Title Brain Sciences. - : MDPI
Roč. 10, č. 9 (2020)Number of pages 11 s. Language eng - English Country CH - Switzerland Keywords polycyclic aromatic hydrocarbons ; OH-PAH metabolites in urine ; psychological tests Subject RIV DN - Health Impact of the Environment Quality OECD category Public and environmental health R&D Projects EF16_019/0000798 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) Method of publishing Open access Institutional support UEM-P - RVO:68378041 UT WOS 000581698700001 EID SCOPUS 85090350933 DOI 10.3390/brainsci10090619 Annotation Objectives: To analyze the impact of polycyclic aromatic hydrocarbons (PAHs) in ambient air at the time of delivery and five years of age on cognitive development in five year old children. Materials and Methods: Two cohorts of children born in the years 2013 and 2014 from Karvina (Northern Moravia, n = 70) and Ceske Budejovice (Southern Bohemia, n = 99) were studied at the age of five years for their cognitive development related to the exposure to PAHs, determined in the ambient air as the concentration of benzo[a]pyrene (B[a]P) and OH-PAH (hydroxy-PAH) metabolites in urine of the newborns at the time of delivery. As psychological tests, the Bender Visual Motor Gestalt Test (BG test) and the Raven Colored Progressive Matrices (RCPM test) were used. Results: Concentrations of B[a]P in the third trimester of mother's pregnancies were 6.1 +/- 4.53 ng/m(3) in Karvina, and 1.19 +/- 1.28 ng/m(3) (p < 0.001) in Ceske Budejovice. Neither the outcome of the RCPM test nor the BG test differed between children in Karvina vs. Ceske Budejovice, or boys vs. girls. Cognitive development in five year old children was affected by the higher exposure to PM2.5 during the third trimester in girls in Karvina. Conclusions: We did not observe any significant effect of prenatal PAH exposure on psychological cognitive tests in five year old children. Workplace Institute of Experimental Medicine Contact Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218 Year of Publishing 2021 Electronic address https://www.mdpi.com/2076-3425/10/9/619
Number of the records: 1