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Increased Microvessel and Arteriole Density in the Contracted Side of the Relapsed Clubfoot
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SYSNO ASEP 0535240 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Increased Microvessel and Arteriole Density in the Contracted Side of the Relapsed Clubfoot Author(s) Novotný, Tomáš (FGU-C) ORCID, RID
Eckhardt, Adam (FGU-C) RID, ORCID
Knitlová, Jarmila (FGU-C) RID, ORCID
Doubková, Martina (FGU-C) ORCID, RID
Ošťádal, M. (CZ)
Uhlík, J. (CZ)
Musílková, Jana (FGU-C) RID, ORCIDSource Title Journal of Pediatric Orthopaedics. - : Lippincott Williams & Wilkins - ISSN 0271-6798
Roč. 40, č. 10 (2020), s. 592-596Number of pages 5 s. Language eng - English Country US - United States Keywords clubfoot ; microvessel density ; arteriole density ; proangiogenic factors ; gene expression ; immunohistochemistry Subject RIV FI - Traumatology, Orthopedics OECD category Orthopaedics R&D Projects NV17-31564A GA MZd - Ministry of Health (MZ) Method of publishing Limited access Institutional support FGU-C - RVO:67985823 UT WOS 000578094000009 EID SCOPUS 85091449211 DOI https://doi.org/10.1097/BPO.0000000000001563 Annotation Clubfoot deformity (pes equinovarus) is one of the most common birth defects, and its etiology is still unknown. Initial clubfoot treatment is based on the Ponseti method throughout most of the world. Despite the effectiveness of this therapy, clubfoot may relapse. Recent studies confirm the theory of active fibrotic remodeling processes in the extracellular matrix of the affected tissue. The aim of this study was to clarify whether relapses in clubfoot therapy are associated with altered angiogenesis and to suggest possible regulatory pathways of this pathologic process. Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2021 Electronic address https://journals.lww.com/pedorthopaedics/Abstract/2020/11000/Increased_Microvessel_and_Arteriole_Density_in_the.17.aspx
Number of the records: 1