Number of the records: 1

Increased Microvessel and Arteriole Density in the Contracted Side of the Relapsed Clubfoot

SYSNO ASEP	0535240
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Increased Microvessel and Arteriole Density in the Contracted Side of the Relapsed Clubfoot
Author(s)	Novotný, Tomáš (FGU-C)_{ORCID, RID} Eckhardt, Adam (FGU-C)_{RID, ORCID} Knitlová, Jarmila (FGU-C)_{RID, ORCID} Doubková, Martina (FGU-C)_{ORCID, RID} Ošťádal, M. (CZ) Uhlík, J. (CZ) Musílková, Jana (FGU-C)_{RID, ORCID}
Source Title	Journal of Pediatric Orthopaedics. - : Lippincott Williams & Wilkins - ISSN 0271-6798 Roč. 40, č. 10 (2020), s. 592-596
Number of pages	5 s.
Language	eng - English
Country	US - United States
Keywords	clubfoot ; microvessel density ; arteriole density ; proangiogenic factors ; gene expression ; immunohistochemistry
Subject RIV	FI - Traumatology, Orthopedics
OECD category	Orthopaedics
R&D Projects	NV17-31564A GA MZd - Ministry of Health (MZ)
Method of publishing	Limited access
Institutional support	FGU-C - RVO:67985823
UT WOS	000578094000009
EID SCOPUS	85091449211
DOI	10.1097/BPO.0000000000001563
Annotation	Clubfoot deformity (pes equinovarus) is one of the most common birth defects, and its etiology is still unknown. Initial clubfoot treatment is based on the Ponseti method throughout most of the world. Despite the effectiveness of this therapy, clubfoot may relapse. Recent studies confirm the theory of active fibrotic remodeling processes in the extracellular matrix of the affected tissue. The aim of this study was to clarify whether relapses in clubfoot therapy are associated with altered angiogenesis and to suggest possible regulatory pathways of this pathologic process.
Workplace	Institute of Physiology
Contact	Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400
Year of Publishing	2021
Electronic address	https://journals.lww.com/pedorthopaedics/Abstract/2020/11000/Increased_Microvessel_and_Arteriole_Density_in_the.17.aspx

Number of the records: 1