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Plate-model applied on concentration effects in size exclusion chromatography
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SYSNO ASEP 0532258 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Plate-model applied on concentration effects in size exclusion chromatography Author(s) Netopilík, Miloš (UMCH-V) RID Source Title Journal of Liquid Chromatography & Related Technologies. - : Taylor & Francis - ISSN 1082-6076
Roč. 43, č. 15-16 (2020), s. 555-561Number of pages 7 s. Language eng - English Country US - United States Keywords concentration effect ; partition coefficient ; separation mechanism Subject RIV CD - Macromolecular Chemistry OECD category Polymer science R&D Projects GC17-04258J GA ČR - Czech Science Foundation (CSF) Method of publishing Limited access Institutional support UMCH-V - RVO:61389013 UT WOS 000558002600001 EID SCOPUS 85089177822 DOI 10.1080/10826076.2019.1703116 Annotation A universal procedure of modeling chromatography separation, based on the plate model, has been developed. On each plate, the equilibrium between the analyte in the mobile and stationary phases is established. This equilibrium may be described by the concentration-dependent partition coefficient. The establishment of the equilibrium on each plate is followed by the displacement of the analyte in the mobile phase by one plate, establishment of new equilibrium, etc. The result is a series of elution curves with positions of maxima dependent on injected mass of the polymer. The procedure has been tested on modeling concentration effects on the basis of dependences of the partition coefficient on local concentrations on each plate. By comparison with the experiment, the slope of the concentration dependence of the partition coefficient of polystyrene in benzene was estimated. It is in qualitative agreement with the literature data obtained by a computer simulation of chromatography separation of polymers in good solvents. Workplace Institute of Macromolecular Chemistry Contact Eva Čechová, cechova@imc.cas.cz ; Tel.: 296 809 358 Year of Publishing 2021 Electronic address https://www.tandfonline.com/doi/full/10.1080/10826076.2019.1703116
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