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Size-Based Sorting of Emulsion Droplets in Microfluidic Channels Patterned with Laser-Ablated Guiding Tracks

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    SYSNO ASEP0525111
    Document TypeJ - Journal Article
    R&D Document TypeJournal Article
    Subsidiary JČlánek ve WOS
    TitleSize-Based Sorting of Emulsion Droplets in Microfluidic Channels Patterned with Laser-Ablated Guiding Tracks
    Author(s) Rehman, A.U. (TR)
    Coskun, U.C. (TR)
    Rashid, Z. (TR)
    Morova, B. (TR)
    Jonáš, Alexandr (UPT-D) RID, SAI, ORCID
    Erten, A. (TR)
    Kiraz, A. (TR)
    Number of authors7
    Source TitleAnalytical Chemistry. - : American Chemical Society - ISSN 0003-2700
    Roč. 92, č. 3 (2020), s. 2597-2604
    Number of pages8 s.
    Publication formPrint - P
    Languageeng - English
    CountryUS - United States
    Keywordsemulsion droplets ; size-based sorting ; laser
    Subject RIVBH - Optics, Masers, Lasers
    OECD categoryOptics (including laser optics and quantum optics)
    Method of publishingLimited access
    Institutional supportUPT-D - RVO:68081731
    UT WOS000511509400034
    EID SCOPUS85079022844
    DOI10.1021/acs.analchem.9b04308
    AnnotationWe demonstrate an autonomous, high-throughput mechanism for sorting of emulsion droplets with different sizes concurrently flowing in a microfluidic Hele-Shaw channel. The aqueous droplets of varying radii suspended in olive oil are separated into different streamlines across the channel upon interaction with a shallow (depth similar to 700 nm) inclined guiding track ablated into the polydimethylsiloxane-coated surface of the channel with focused femtosecond laser pulses. Specifically, the observed differences in the droplet trajectories along the guiding track arise due to the different scaling of the confinement force attracting the droplets into the track, fluid drag, and wall friction, with the droplet radius. In addition, the distance traveled by the droplets along the track also depends on the track width, with wider tracks providing more stable droplet guiding for any given droplet size. We systematically study the influence of the droplet size and velocity on the trajectory of the droplets in the channel and analyze the sensitivity of size-based droplet sorting for varying flow conditions. The droplet guiding and sorting experiments are complemented by modeling of the droplet motion in the channel flow using computational fluid dynamics simulations and a previously developed model of droplet guiding. Finally, we demonstrate a complete separation of droplets produced by fusion of two independent droplet streams at the inlet of the Hele-Shaw channel from unfused daughter droplets. The presented droplet sorting technique can find applications in the development of analytical and preparative microfluidic protocols.
    WorkplaceInstitute of Scientific Instruments
    ContactMartina Šillerová, sillerova@ISIBrno.Cz, Tel.: 541 514 178
    Year of Publishing2021
    Electronic addresshttps://pubs.acs.org/doi/abs/10.1021/acs.analchem.9b04308
Number of the records: 1  

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