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Polypeptides for the treatment of autoimmune diseases based on blocking the p19 subunit of the IL-23 human cytokine

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    SYSNO ASEP0523549
    Document TypeP - Patent
    R&D Document TypePatent or other outcome protected by special legislation
    TitlePolypeptides for the treatment of autoimmune diseases based on blocking the p19 subunit of the IL-23 human cytokine
    Author(s) Malý, Petr (BTO-N) RID, ORCID
    Křížová, Lucie (BTO-N)
    Kuchař, Milan (BTO-N) RID
    Petroková, Hana (BTO-N) RID
    Year of issue2019
    Possible third party use of the resultA - Pro využití výsledku jiným subjektem je vždy nutné nabytí licence
    Royalty requestedZ - Poskytovatel licence nepožaduje v některých případech licenční poplatek
    Patent no. or utility model no. or industrial design no.307849B6
    Date of the patent acceptance15.05.2019
    Name of the patent ownerBiotechnologický ústav AV ČR, v. v. i.
    Code of the issuer nameCZ001 - Úřad průmyslového vlastnictví Prague
    Current useA - Pouze udělený (dosud nevyužívaný) patent nebo patent využívaný jeho vlastníkem
    Languageeng - English
    Keywordsp19 subunit ; amino acids P, A, T, M, Q ; IL-23 human cytokine
    Subject RIVEB - Genetics ; Molecular Biology
    OECD categoryBiochemistry and molecular biology
    Institutional supportBTO-N - RVO:86652036
    AnnotationThe invention concerns a polypeptide suitable for treating autoimmune diseases comprising an amino acid sequence: XYKNXINXAXXVXXVKXXIDXILAXILAXLP (SEW ID NO. 1) with an alpha-helical structure directly attached to the N-terminus or C-terminus, where: X 1 is selected from amino acids V, I, P, S ., Xis selected from amino acids T, W, R, L, M, Xis selected from amino acids P, A, T, M, Q, Xis selected from amino acids A, S, G, V, Xis selected from amino acids W, G, T, F, L, Xis selected from amino acids L, R, A, Xis selected from amino acids A, H, L, Y, R, Xis selected from amino acids R, S, Xis selected from amino acids M, C, W, R, F, Xis selected from amino acids R, M, L, S, V, Xis selected from amino acids N, A, G, P, R.
    WorkplaceInstitute of Biotechnology
    ContactMonika Kopřivová, Monika.Koprivova@ibt.cas.cz, Tel.: 325 873 700
    Year of Publishing2020
    Electronic addresshttps://cz.espacenet.com/advancedSearch?locale=cz_CZ
Number of the records: 1