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Polypeptides for the treatment of autoimmune diseases based on blocking the p19 subunit of the IL-23 human cytokine
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SYSNO ASEP 0523549 Document Type P - Patent R&D Document Type Patent or other outcome protected by special legislation Title Polypeptides for the treatment of autoimmune diseases based on blocking the p19 subunit of the IL-23 human cytokine Author(s) Malý, Petr (BTO-N) RID, ORCID
Křížová, Lucie (BTO-N)
Kuchař, Milan (BTO-N) RID
Petroková, Hana (BTO-N) RIDYear of issue 2019 Possible third party use of the result A - Pro využití výsledku jiným subjektem je vždy nutné nabytí licence Royalty requested Z - Poskytovatel licence nepožaduje v některých případech licenční poplatek Patent no. or utility model no. or industrial design no. 307849B6 Date of the patent acceptance 15.05.2019 Name of the patent owner Biotechnologický ústav AV ČR, v. v. i. Code of the issuer name CZ001 - Úřad průmyslového vlastnictví Prague Current use A - Pouze udělený (dosud nevyužívaný) patent nebo patent využívaný jeho vlastníkem Language eng - English Keywords p19 subunit ; amino acids P, A, T, M, Q ; IL-23 human cytokine Subject RIV EB - Genetics ; Molecular Biology OECD category Biochemistry and molecular biology Institutional support BTO-N - RVO:86652036 Annotation The invention concerns a polypeptide suitable for treating autoimmune diseases comprising an amino acid sequence: XYKNXINXAXXVXXVKXXIDXILAXILAXLP (SEW ID NO. 1) with an alpha-helical structure directly attached to the N-terminus or C-terminus, where: X 1 is selected from amino acids V, I, P, S ., Xis selected from amino acids T, W, R, L, M, Xis selected from amino acids P, A, T, M, Q, Xis selected from amino acids A, S, G, V, Xis selected from amino acids W, G, T, F, L, Xis selected from amino acids L, R, A, Xis selected from amino acids A, H, L, Y, R, Xis selected from amino acids R, S, Xis selected from amino acids M, C, W, R, F, Xis selected from amino acids R, M, L, S, V, Xis selected from amino acids N, A, G, P, R. Workplace Institute of Biotechnology Contact Monika Kopřivová, Monika.Koprivova@ibt.cas.cz, Tel.: 325 873 700 Year of Publishing 2020 Electronic address https://cz.espacenet.com/advancedSearch?locale=cz_CZ
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