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The distribution of epigenetic histone marks differs between the X and Y chromosomes in Silene latifolia

SYSNO ASEP	0509308
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	The distribution of epigenetic histone marks differs between the X and Y chromosomes in Silene latifolia
Author(s)	Bačovský, Václav (BFU-R)_ORCID Houben, A. (DE) Kumke, K. (DE) Hobza, Roman (BFU-R)_{RID, ORCID}
Number of authors	4
Source Title	Planta. - : Springer - ISSN 0032-0935 Roč. 250, č. 2 (2019), s. 487-494
Number of pages	8 s.
Publication form	Print - P
Language	eng - English
Country	DE - Germany
Keywords	plant chromosomes ; sex-chromosomes ; chromatin-structure
Subject RIV	EF - Botanics
OECD category	Plant sciences, botany
R&D Projects	GA18-06147S GA ČR - Czech Science Foundation (CSF)
	GA16-08698S GA ČR - Czech Science Foundation (CSF)
Method of publishing	Limited access
Institutional support	BFU-R - RVO:68081707
UT WOS	000474429800007
DOI	10.1007/s00425-019-03182-7
Annotation	Main conclusionContrasting patterns of histone modifications between the X and Y chromosome in Silene latifolia show euchromatic histone mark depletion on the Y chromosome and indicate hyperactivation of one X chromosome in females.AbstractSilene latifolia (white campion) is a dioecious plant with heteromorphic sex chromosomes (24, XX in females and 24, XY in males), and a genetically degenerated Y chromosome that is 1.4 times larger than the X chromosome. Although the two sex chromosomes differ in their DNA content, information about epigenetic histone marks and evidence of their function are scarce. We performed immunolabeling experiments using antibodies specific for active and suppressive histone modifications as well as pericentromere-specific histone modifications. We show that the Y chromosome is partially depleted of histone modifications important for transcriptionally active chromatin, and carries these marks only in the pseudo-autosomal region, but that it is not enriched for suppressive and pericentromere histone marks. We also show that two of the active marks are specifically enriched in one of the X chromosomes in females and in the X chromosome in males. Our data support recent findings that genetic imprinting mediates dosage compensation of sex chromosomes in S. latifolia.
Workplace	Institute of Biophysics
Contact	Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244
Year of Publishing	2020
Electronic address	https://link.springer.com/article/10.1007%2Fs00425-019-03182-7

Number of the records: 1