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Amalgam Electrodes Pretreatment and Electrochemical Analysis of DNA
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SYSNO ASEP 0506671 Document Type C - Proceedings Paper (int. conf.) R&D Document Type Conference Paper Title Amalgam Electrodes Pretreatment and Electrochemical Analysis of DNA Author(s) Daňhel, Aleš (BFU-R) RID, ORCID
Fojta, Miroslav (BFU-R) RID, ORCIDNumber of authors 2 Source Title XXXVI. Moderní elektrochemické metody. Sborník přednášek. - Ústí nad Labem : Best servis, 2016 / Navrátil T. ; Fojta M. ; Schwarzová K. - ISBN 978-80-905221-4-5 Pages č. 2016 (2016), s. 32-36 Number of pages 5 s. Publication form Print - P Action Moderní elektrochemické metody /36./ Event date 23.05.2016 - 27.05.2016 VEvent location Jetřichovice Country CZ - Czech Republic Event type WRD Language eng - English Country CZ - Czech Republic Keywords double-helical polynucleotides ; electrically charged surfaces ; mercury-electrode ; silver amalgam Subject RIV CF - Physical ; Theoretical Chemistry OECD category Physical chemistry R&D Projects GA16-01625S GA ČR - Czech Science Foundation (CSF) Institutional support BFU-R - RVO:68081707 UT WOS 000389898200006 Annotation Mercury meniscus silver solid amalgam electode (m-AgSAE) represents the most suitable and perspective alternative to mercury electrodes which excel in sensitivity to biopolymers and their structural changes. This work briefly summarizes factors influencing electrochemical analysis of DNA at mercury and amalgam electrodes and it is mainly devoted to development of suitable pretreatment procedure, which could securte repeatable and reliable measurements of DNA at m-AgSAes. The results are essential for further utilization of amalgam electrodes in developement of biosensors, since DNA samples are very strongly adsorbed at the electrodes, and none pretreatment procedure was found to be successful in their complete desorption. Workplace Institute of Biophysics Contact Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244 Year of Publishing 2020
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