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Laser-accelerated proton beams from a solid hydrogen target as a future source of radionuclides for positron emission tomography
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SYSNO ASEP 0501410 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Ostatní články Title Laser-accelerated proton beams from a solid hydrogen target as a future source of radionuclides for positron emission tomography Author(s) Italiano, A. (IT)
Amato, E. (IT)
Margarone, Daniele (FZU-D) RID, ORCID
Pšikal, Jan (FZU-D) RID, ORCID
Korn, Georg (FZU-D) RID, ORCIDSource Title Journal of Scientific and Engineering Research
Roč. 4, č. 11 (2017), s. 173-176Number of pages 4 s. Language eng - English Country IN - India Keywords laser ; particle acceleration ; positron emission tomography ; Extreme Laser Infrastructure Subject RIV BL - Plasma and Gas Discharge Physics OECD category Fluids and plasma physics (including surface physics) R&D Projects EF16_019/0000789 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) LQ1606 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) Institutional support FZU-D - RVO:68378271 Annotation The production of radionuclides for positron emission tomography through future laser-accelerated proton beams is an interesting perspective. We evaluated the production yields that can be expected according to a new source term based on three-dimensional particle-in-cell (PIC) simulations of the laser available at ELI-Beamlines interacting with an innovative cryogenic hydrogen target. Results indicate that 370 MBq activity can be reached within a few minutes of irradiation for the four conventional PET nuclides 18F, 11C, 13N and 15O, and for several heavier positron emitters, such as 60Cu, 62Cu, 63Zn, 68Ga and 73Se, currently used in pre-clinical and clinical studies. Workplace Institute of Physics Contact Kristina Potocká, potocka@fzu.cz, Tel.: 220 318 579 Year of Publishing 2019
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