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Improving quality of optical fiber-based endoscopy for in vivo brain imaging

SYSNO ASEP	0501208
Document Type	A - Abstract
R&D Document Type	The record was not marked in the RIV
R&D Document Type	Není vybrán druh dokumentu
Title	Improving quality of optical fiber-based endoscopy for in vivo brain imaging
Author(s)	Tučková, Tereza (UPT-D)_ORCID Hons, Miroslav (UPT-D)_ORCID Jákl, Petr (UPT-D)_{RID, ORCID, SAI} Šiler, Martin (UPT-D)_{RID, ORCID, SAI} Dražanová, Eva (UPT-D)_{RID, ORCID, SAI} Krátká, Lucie (UPT-D)_{RID, ORCID, SAI} Traegaardh, Johanna (UPT-D)_{RID, ORCID, SAI} Pikálek, Tomáš (UPT-D)_{RID, ORCID, SAI} Simpson, Stephen Hugh (UPT-D)_{RID, SAI} Tyc, Tomáš (UPT-D)_ORCID Uhlířová, Hana (UPT-D)_{ORCID, RID} Čižmár, Tomáš (UPT-D)_{RID, ORCID, SAI}
Number of authors	12
Source Title	Neuroscience v2018. Book of Abstracts. - Washington : SFN, 2018
Number of pages	1 s.
Publication form	Print - P
Action	Neuroscience 2018
Event date	03.11.2018 - 07.11.2018
VEvent location	San Diego
Country	US - United States
Event type	WRD
Language	eng - English
Country	US - United States
R&D Projects	EF15_003/0000476 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
Institutional support	UPT-D - RVO:68081731
Annotation	Optical fibers have been used in the past to image in locations deep in the scattering tissue which are not accessible through optical microscopy. Recently, the endeavor to minimize tissue damage has motivated the use of multi-mode fibers which allowed for high-resolution imaging with significantly smaller cross-section than single-mode fibers or GRIN lenses. Only recently the first successful functional imaging of neuronal calcium in vivo has been demonstrated in the mouse brain. These efforts represent a huge leap forward in MMF-based endoscopy, yet the quality of the detected functional calcium signals in vivo is still far from the state-of-the-art standards set by confocal and multi-photon microscopy. We introduce here computational and technological advancements to improve the quality of fiber-based imaging potentially important for brain endoscopy.
Workplace	Institute of Scientific Instruments
Contact	Martina Šillerová, sillerova@ISIBrno.Cz, Tel.: 541 514 178
Year of Publishing	2019

Number of the records: 1