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Synthesis of Steroid Derivatives for In Vitro Diagnostics.
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SYSNO ASEP 0496998 Document Type C - Proceedings Paper (int. conf.) R&D Document Type The record was not marked in the RIV Title Synthesis of Steroid Derivatives for In Vitro Diagnostics. Author(s) Kos, Martin (UCHP-M) RID, ORCID, SAI
Váňa, Lubomír (UCHP-M)
Žádný, Jaroslav (UCHP-M) RID, SAI, ORCID
Storch, Jan (UCHP-M) RID, ORCID, SAIArticle number P 32 Source Title Book of Abstracts. - Louvain-la-Neuve : Université catholique de Louvain, 2018 / Gaigneux E. - ISBN N Pages s. 6 Number of pages 1 s. Publication form Print - P Action Advances in Organic, Bioorganic and Pharmaceutical Chemistry LIBLICE 2018 /53./ Event date 02.11.2018 - 04.11.2018 VEvent location Lázně Bělohrad Country CZ - Czech Republic Event type EUR Language eng - English Country CZ - Czech Republic Keywords steriod ; dyagnostics ; sythesis Subject RIV CC - Organic Chemistry OECD category Organic chemistry R&D Projects FV20061 GA MPO - Ministry of Industry and Trade (MPO) Institutional support UCHP-M - RVO:67985858 Annotation This work is focused on the synthesis of novel steroidal androgen derivatives consisting of a steroidal skeleton, a spacer and imidazole ring or a primary amine functional group. The starting material for the synthesis is represented by commercial available hydroxy-androgens, which are further modified. First, the hydroxyl group is attached to the spacer and then connected to the desired imidazole or the protected primary amine. The above described derivatives will be utilized for development of analytical kits for a determination of the free steroid hormone. Workplace Institute of Chemical Process Fundamentals Contact Eva Jirsová, jirsova@icpf.cas.cz, Tel.: 220 390 227 Year of Publishing 2019
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