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Chemico-physical and pharmacodynamic properties of extracellular Dictyosphaerium chlorelloides biopolymer

SYSNO ASEP	0493063
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Chemico-physical and pharmacodynamic properties of extracellular Dictyosphaerium chlorelloides biopolymer
Author(s)	Halaj, M. (SK) Matulová, M. (SK) Šutovská, M. (SK) Barboríková, J. (SK) Kazimierová, I. (SK) Fraňová, S. (SK) Přibyl, Pavel (BU-J)_{RID, ORCID} Cepák, Vladislav (BU-J)_RID Lukavský, Jaromír (BU-J)_{RID, ORCID} Capek, P. (SK)
Source Title	Carbohydrate Polymers. - : Elsevier - ISSN 0144-8617 Roč. 198, OCT 15 2018 (2018), s. 215-224
Number of pages	10 s.
Language	eng - English
Country	GB - United Kingdom
Keywords	Biopolymer ; Green microalgae ; O-methylated galactoses
Subject RIV	CD - Macromolecular Chemistry
OECD category	Polymer science
R&D Projects	TE01020080 GA TA ČR - Technology Agency of the Czech Republic (TA ČR)
Institutional support	BU-J - RVO:67985939
UT WOS	000440785200026
EID SCOPUS	85048888591
DOI	10.1016/j.carbpol.2018.06.018
Annotation	Green microalga Dictyosphaerium chlorelloides was found to be a significant producer of the extracellular biopolymer, a potential fytochemical with pharmacodynamic properties. Dominant components of the biopolymer were found to be Gal (39 wt%) with its methyl derivatives (15 wt%), Rha (19 wt%) and Man (14 wt%). NMR spectroscopy revealed complex structure with galactan backbone branched by sugars in furano and pyrano forms in alpha and beta configurations. Biopolymer antitussive effect was similar to that of centrally acting antitussive drugs, indicating its relatively good antitussive potential.
Workplace	Institute of Botany
Contact	Martina Bartošová, martina.bartosova@ibot.cas.cz, ibot@ibot.cas.cz, Tel.: 271 015 242 ; Marie Jakšová, marie.jaksova@ibot.cas.cz, Tel.: 384 721 156-8
Year of Publishing	2019

Number of the records: 1