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Beta-glucans and cholesterol
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SYSNO ASEP 0488761 Document Type J - Journal Article R&D Document Type The record was not marked in the RIV Subsidiary J Článek ve WOS Title Beta-glucans and cholesterol Author(s) Šíma, Petr (MBU-M)
Vannucci, Luca (MBU-M) RID, ORCID
Větvička, V. (US)Source Title International Journal of Molecular Medicine. - : Spandidos Publications - ISSN 1107-3756
Roč. 41, č. 4 (2018), s. 1799-1808Number of pages 10 s. Language eng - English Country GR - Greece Keywords cholesterol ; beta-glucans ; diet Subject RIV EE - Microbiology, Virology OECD category Microbiology Method of publishing Open access Institutional support MBU-M - RVO:61388971 UT WOS 000427160600001 EID SCOPUS 85041557156 DOI 10.3892/ijmm.2018.3411 Annotation Hypercholesterolemia is one of primary risk factors of cardiovascular disease, together with metabolic syndrome, hypertension and diabetes. Although progress has been made, the search for novel methods of preventing and treating dyslipidemia is ongoing and current therapies for cardiovascular disease induce various side effects. -glucans are linear unbranched polysaccharides found in various natural sources, such as mushrooms. Due to their structure they are able to interact with innate immunity receptors, however they also act as dietary fibers in the digestive tract. As there are two forms of -glucans, insoluble and soluble forms, they are able to interact with lipids and biliary salts in the bowel and consequently reduce cholesterol levels. Therefore, they may be developed as a suitable therapeutic option to treat patients with dyslipidemia, as they are natural molecules that do not induce any significant side effects. The current review discusses the evidence supporting the effects of -glucans on cholesterol levels.
Workplace Institute of Microbiology Contact Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231 Year of Publishing 2021 Electronic address https://www.spandidos-publications.com/10.3892/ijmm.2018.3411
Number of the records: 1