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Carborane-linked 2'-deoxyuridine 5'-O-triphosphate as building block for polymerase synthesis of carborane-modified DNA

SYSNO ASEP	0482517
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Carborane-linked 2'-deoxyuridine 5'-O-triphosphate as building block for polymerase synthesis of carborane-modified DNA
Author(s)	Balintová, Jana (UOCHB-X)_RID Simonova, Anna (UOCHB-X) Bialek-Pietras, M. (PL) Olejniczak, A. (PL) Lesnikowski, Z. J. (PL) Hocek, Michal (UOCHB-X)_{RID, ORCID}
Source Title	Bioorganic and Medicinal Chemistry Letters. - : Elsevier - ISSN 0960-894X Roč. 27, č. 21 (2017), s. 4786-4788
Number of pages	3 s.
Language	eng - English
Country	GB - United Kingdom
Keywords	nucleotides ; nucleoside triphosphates ; carboranes ; DNA polymerase ; oligonucleotides
Subject RIV	CC - Organic Chemistry
OECD category	Organic chemistry
R&D Projects	GBP206/12/G151 GA ČR - Czech Science Foundation (CSF)
Institutional support	UOCHB-X - RVO:61388963
UT WOS	000413998900002
EID SCOPUS	85030636561
DOI	10.1016/j.bmcl.2017.09.064
Annotation	5-[(p-Carborane-2-yl) ethynyl]-2'-deoxyuridine 5'-O-triphosphate was synthesized and used as a good substrate in enzymatic construction of carborane-modified DNA or oligonucleotides containing up to 21 carborane moieties in primer extension reactions by DNA polymerases.
Workplace	Institute of Organic Chemistry and Biochemistry
Contact	asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Viktorie Chládková, Tel.: 232 002 434
Year of Publishing	2018

Number of the records: 1