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Tuning Surface Chemistry of Polyetheretherketone by Gold Coating and Plasma Treatment
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SYSNO ASEP 0480070 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Tuning Surface Chemistry of Polyetheretherketone by Gold Coating and Plasma Treatment Author(s) Novotná, Z. (CZ)
Rimpelová, S. (CZ)
Juřík, P. (CZ)
Veselý, M. (CZ)
Kolská, Z. (CZ)
Hubáček, Tomáš (BC-A) RID
Borovec, Jakub (BC-A) RID
Švorčík, V. (CZ)Number of authors 8 Article number 424 Source Title Nanoscale Research Letters. - : Springer - ISSN 1931-7573
Roč. 12, JUN (2017)Number of pages 9 s. Language eng - English Country US - United States Keywords polyetheretherketone ; plasma treatment ; gold sputtering ; atomic force microscopy Subject RIV JJ - Other Materials OECD category Materials engineering R&D Projects LM2015075 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) Institutional support BC-A - RVO:60077344 UT WOS 000404812200001 EID SCOPUS 85021669411 DOI 10.1186/s11671-017-2182-x Annotation Polyetheretherketone (PEEK) has good chemical and biomechanical properties that are excellent for biomedical applications. However, PEEK exhibits hydrophobic and other surface characteristics which cause limited cell adhesion. We have investigated the potential of Ar plasma treatment for the formation of a nanostructured PEEK surface in order to enhance cell adhesion. The specific aim of this study was to reveal the effect of the interface of plasma-treated and gold-coated PEEK matrices on adhesion and spreading of mouse embryonic fibroblasts. The surface characteristics (polarity, surface chemistry, and structure) before and after treatment were evaluated by various experimental techniques (gravimetry, goniometry, X-ray photoelectron spectroscopy (XPS), and electrokinetic analysis). Further, atomic force microscopy (AFM) was employed to examine PEEK surface morphology and roughness. The biological response of cells towards nanostructured PEEK was evaluated in terms of cell adhesion, spreading, and proliferation. Detailed cell morphology was evaluated by scanning electron microscopy (SEM). Compared to plasma treatment, gold coating improved PEEK wettability. The XPS method showed a decrease in the carbon concentration with increasing time of plasma treatment. Cell adhesion determined on the interface between plasma-treated and gold-coated PEEK matrices was directly proportional to the thickness of a gold layer on a sample. Our results suggest that plasma treatment in a combination with gold coating could be used in biomedical applications requiring enhanced cell adhesion. Workplace Biology Centre (since 2006) Contact Dana Hypšová, eje@eje.cz, Tel.: 387 775 214 Year of Publishing 2018
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