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Progress in biocatalysis with immobilized viable whole cells: systems development, reaction engineering and applications
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SYSNO ASEP 0479465 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Progress in biocatalysis with immobilized viable whole cells: systems development, reaction engineering and applications Author(s) Polakovič, M. (SK)
Švitel, J. (SK)
Bučko, M. (SK)
Filip, J. (CZ)
Neděla, Vilém (UPT-D) RID, ORCID, SAI
Ansorge-Schumacher, M.B. (DE)
Gemeiner, P. (SK)Number of authors 7 Source Title Biotechnology Letters. - : Springer - ISSN 0141-5492
Roč. 39, č. 5 (2017), s. 667-683Number of pages 17 s. Publication form Print - P Language eng - English Country NL - Netherlands Keywords biocatalysis ; immobilization methods ; immobilized whole-cell biocatalyst ; multienzyme cascade reactions ; process economics ; reaction engineering Subject RIV JA - Electronics ; Optoelectronics, Electrical Engineering OECD category Bioprocessing technologies (industrial processes relying on biological agents to drive the process) biocatalysis, fermentation Institutional support UPT-D - RVO:68081731 UT WOS 000400388100003 EID SCOPUS 85011798906 DOI 10.1007/s10529-017-2300-y Annotation Viable microbial cells are important biocatalysts in the production of fine chemicals and biofuels, in environmental applications and also in emerging applications such as biosensors or medicine. Their increasing significance is driven mainly by the intensive development of high performance recombinant strains supplying multienzyme cascade reaction pathways, and by advances in preservation of the native state and stability of whole-cell biocatalysts throughout their application. In many cases, the stability and performance of whole-cell biocatalysts can be highly improved by controlled immobilization techniques. This review summarizes the current progress in the development of immobilized whole-cell biocatalysts, the immobilization methods as well as in the bioreaction engineering aspects and economical aspects of their biocatalytic applications. Workplace Institute of Scientific Instruments Contact Martina Šillerová, sillerova@ISIBrno.Cz, Tel.: 541 514 178 Year of Publishing 2018
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