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Novel Biomaterials in Regenerative Medicine
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SYSNO ASEP 0475918 Document Type M - Monograph Chapter R&D Document Type Monograph Chapter Title Labeling Efficiency and Viability of Stem Cells Cultured with Poly-L-Lysine coated Iron Oxide Nanoparticles Author(s) Jendelová, Pavla (UEM-P) RID, ORCID
Syková, Eva (UEM-P) RIDSource Title Novel Biomaterials in Regenerative Medicine. - 2016 : Epika, 2016 / Caraglia Michele ; Desiderio Vincenzo - ISBN 978-80-88113-69-0 Pages s. 62-77 Number of pages 16 s. Number of pages 276 Publication form Print - P Language eng - English Country CZ - Czech Republic Keywords cell labelling ; stem cell tracking ; cell viability ; iron oxide nanoparticles Subject RIV FP - Other Medical Disciplines OECD category Biochemical research methods R&D Projects LO1309 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) Institutional support UEM-P - RVO:68378041 Annotation Newly developed Poly-L-Lysine coated superparamagnetic iron oxide nanoparticles (PCSPIO) were compared with dextran coated superparamagnetic iron oxide nanoparticles DCSPIO (Endorem®) for cytotoxicity and labeling efficiency in mesenchymal stem cells (MSCs), olfactory ensheathing cells (OECs) and chondrocytes (CHONCs) i.e. in cell most often used in human medicine. PCSPIO labeling was more efficient and more cells remained viable when compared to DCSPIO Workplace Institute of Experimental Medicine Contact Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218 Year of Publishing 2018
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