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Presynaptic Spontaneous Activity Enhances the Accuracy of Latency Coding

SYSNO ASEP	0464967
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Presynaptic Spontaneous Activity Enhances the Accuracy of Latency Coding
Author(s)	Leváková, Marie (FGU-C)_{RID, ORCID} Tamborrino, M. (AT) Košťál, Lubomír (FGU-C)_{RID, ORCID, SAI} Lánský, Petr (FGU-C)_{RID, ORCID}
Source Title	Neural Computation - ISSN 0899-7667 Roč. 28, č. 10 (2016), s. 2162-2180
Number of pages	19 s.
Language	eng - English
Country	US - United States
Keywords	neural coding ; first-spike latency ; spontaneous activity
Subject RIV	FH - Neurology
R&D Projects	7AMB15AT010 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
	GA15-08066S GA ČR - Czech Science Foundation (CSF)
Institutional support	FGU-C - RVO:67985823
UT WOS	000384452300006
EID SCOPUS	84988615474
DOI	10.1162/NECO_a_00880
Annotation	The time to the first spike after stimulus onset typically varies with the stimulation intensity. Experimental evidence suggests that neural systems use such response latency to encode information about the stimulus. We investigate the decoding accuracy of the latency code in relation to the level of noise in the form of presynaptic spontaneous activity. Paradoxically, the optimal performance is achieved at a nonzero level of noise and suprathreshold stimulus intensities. We argue that this phenomenon results from the influence of the spontaneous activity on the stabilization of the membrane potential in the absence of stimulation. The reported decoding accuracy improvement represents a novel manifestation of the noise-aided signal enhancement.
Workplace	Institute of Physiology
Contact	Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400
Year of Publishing	2017

Number of the records: 1