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Silica-coated manganite and Mn-based ferrite nanoparticles: a comparative study focused on cytotoxicity
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SYSNO ASEP 0461365 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Silica-coated manganite and Mn-based ferrite nanoparticles: a comparative study focused on cytotoxicity Author(s) Kaman, Ondřej (FZU-D) RID, ORCID
Dědourková, T. (CZ)
Koktan, Jakub (FZU-D) RID
Kuličková, Jarmila (FZU-D) ORCID
Maryško, Miroslav (FZU-D) RID
Veverka, Pavel (FZU-D) RID, ORCID
Havelek, R. (CZ)
Královec, K. (CZ)
Turnovcová, Karolína (UEM-P) ORCID
Jendelová, Pavla (UEM-P) RID, ORCID
Schröfel, A. (CZ)
Svoboda, L. (CZ)Article number 100 Source Title Journal of Nanoparticle Research. - : Springer - ISSN 1388-0764
Roč. 18, č. 4 (2016), 1-18Number of pages 18 s. Language eng - English Country NL - Netherlands Keywords magnetic nanoparticles ; manganite ; ferrite ; in vitro toxicity ; stem cells Subject RIV BM - Solid Matter Physics ; Magnetism OECD category Condensed matter physics (including formerly solid state physics, supercond.) Subject RIV - cooperation Institute of Experimental Medicine - Genetics ; Molecular Biology R&D Projects GA15-10088S GA ČR - Czech Science Foundation (CSF) Institutional support FZU-D - RVO:68378271 ; UEM-P - RVO:68378041 UT WOS 000373861400006 EID SCOPUS 84962745880 DOI 10.1007/s11051-016-3402-5 Annotation In vitro toxicity of manganite nanoparticles was thoroughly analysed and compared with Mn-Zn ferrite nanoparticles. Nanoparticles of La0.63Sr0.37MnO3 manganite were prepared by two distinct methods, namely the molten salt synthesis and the traditional sol-gel route, whereas nanoparticles of Mn0.61Zn0.42Fe1.97O4 ferrite, selected as a comparative material, were synthesized by a new procedure under hydrothermal conditions. Magnetic cores were coated with silica, and several samples of manganite nanoparticles with different thicknesses of silica shell were prepared. The products were analysed by using TEM, DLS, measurement of the zeta-potential measurements, IR spectroscopy, and SQUID magnetometry. The silica-coated products were subjected to a robust evaluation of their cytotoxicity by four different methods. The results clearly indicated superior properties of the Mn-Zn ferrite. Workplace Institute of Physics Contact Kristina Potocká, potocka@fzu.cz, Tel.: 220 318 579 Year of Publishing 2017
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