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Biological evaluation of ultra-fine titanium with improved mechanical strength for dental implant engineering

SYSNO ASEP	0456259
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Biological evaluation of ultra-fine titanium with improved mechanical strength for dental implant engineering
Author(s)	Ostrovská, L. (CZ) Vištejnová, L. (CZ) Dzugan, J. (CZ) Slama, P. (CZ) Kubina, T. (CZ) Ukraintsev, Egor (FZU-D)_{RID, ORCID} Kubies, Dana (UMCH-V)_{RID, ORCID} Králíčková, M. (CZ) Hubálek Kalbáčová, M. (CZ)
Source Title	Journal of Materials Science. - : Springer - ISSN 0022-2461 Roč. 51, č. 6 (2016), s. 3097-3110
Number of pages	14 s.
Language	eng - English
Country	US - United States
Keywords	mesenchymal stem-cells ; thermal-stability
Subject RIV	BO - Biophysics
Subject RIV - cooperation	Institute of Macromolecular Chemistry - Macromolecular Chemistry
R&D Projects	ED1.1.00/02.0109 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
	NT13297 GA MZd - Ministry of Health (MZ)
Institutional support	FZU-D - RVO:68378271 ; UMCH-V - RVO:61389013
UT WOS	000367681300030
EID SCOPUS	84953367658
DOI	10.1007/s10853-015-9619-3
Annotation	Titanium, the gold standard for dental implant materials, is distinguished by its exceptional biocompatibility; however, from a long-term perspective, titanium still lacks sufficient loading strength. Commercially pure titanium with grain size 30 mu m was processed by equal channel angular pressing, and two novel mechanically improved types of titanium material with grain size 4.6 and a parts per thousand currency sign1 A mu m were obtained. The surfaces of these ultra-fine grained titanium samples were further mechanically treated by grinding and polishing, and their surfaces were characterized by atomic force microscopy and contact angle measurement. Osteoblast-like cells and human mesenchymal stem cells were used to evaluate the cytocompatibility of these titanium samples. The cell metabolic activity, cell number, cell area, morphology, and cell adhesion quality during the early stage (2 h) and prolonged cultivation (48 h) were determined.
Workplace	Institute of Physics
Contact	Kristina Potocká, potocka@fzu.cz, Tel.: 220 318 579
Year of Publishing	2016

Number of the records: 1